Hs01230328_cn

• Gene Symbol: SIX6
• Assay Reference Genome Location: Chr.14:60511110 on build GRCh38
• Cytoband: 14q23.1

Target Gene Details

• Entrez Gene ID: 4990
• Gene Name: SIX homeobox 6
• Gene Aliases: MCOPCT2, ODRMD, OPTX2, Six9
• Location: Chr.14:60509220-60511807 on Build GRCh38
• Assay Gene Location: Overlaps Intron 1 - Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SIX6	NM_007374.2			NP_031400.2
	AJ011785.1			CAA09773.1
	BC065831.1			AAH65831.1
	BC069413.1			AAH69413.2
	BC087852.1			AAH87852.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv564880	Chr.14:60397865 - 60916029 on Build GRCh38	Gain	SIX4 SALRNA1 SIX1 LOC105378189 C14orf39 SIX6 MNAT1
nsv564881	Chr.14:60457291 - 61377535 on Build GRCh38	Gain	SIX4 SALRNA1 SIX1 PRKCH TMEM30B SLC38A6 LOC105378189 TRMT5 C14orf39 SIX6 MNAT1

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

homeodomain transcription factor

Gene Ontology Categories:

Process(es)

eye development
transcription from RNA polymerase II promoter
visual perception
organ morphogenesis
positive regulation of transcription from RNA polymerase II promoter

Function(s)

transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
DNA binding