Hs01238232_cn

• Gene Symbol: HOXB-AS3
• Assay Reference Genome Location: Chr.17:48592250 on build GRCh38
• Cytoband: 17q21.32

Target Gene Details

• Entrez Gene ID: 404266
• Gene Name: HOXB cluster antisense RNA 3
• Gene Aliases: -
• Location: Chr.17:48590420-48606414 on Build GRCh38
• Assay Gene Location: Overlaps Intron 1 - Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
HOXB-AS3	NR_033201.2
	NR_033202.2
	NR_033203.1
	NR_033204.2
	NR_110329.1
	NR_110331.1
	AA299267.1
	BF431268.1
	CB046509.1
	CF127739.1
	DA741273.1
	W39335.1

Target Gene Details

• Entrez Gene ID: 3215
• Gene Name: homeobox B5
• Gene Aliases: HHO.C10, HOX2, HOX2A, HU-1, Hox2.1
• Location: Chr.17:48591257-48593741 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
HOXB5	NM_002147.3	2	828	NP_002138.1
	AK314964.1	2	885
	BC117247.1	2	789
	BE621135.1
	M86726.1	1	122	AAB59430.1
	M92299.1	2	1044	AAA52682.1
	X03794.1	1	172	CAA27420.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833471	Chr.17:48540425 - 48705983 on Build GRCh38	Gain	HOXB8 MIR10A HOXB9 HOXB-AS1 MIR196A1 HOXB7 HOXB-AS3 HOXB2 LOC105371809 HOXB5 HOXB6 HOXB3 HOXB4
dgv5676n54	Chr.17:48539657 - 48627174 on Build GRCh38	Loss	HOXB8 HOXB7 HOXB-AS3 MIR10A HOXB9 HOXB2 HOXB5 HOXB6 HOXB-AS1 HOXB3 HOXB4
nsv833469	Chr.17:48414487 - 48632044 on Build GRCh38	Loss	HOXB8 MIR10A HOXB9 HOXB-AS1 HOXB7 HOXB-AS3 LOC101927166 HOXB2 HOXB5 SKAP1 HOXB6 HOXB1 HOXB3 HOXB4
esv2758694	Chr.17:48525311 - 48759475 on Build GRCh38	Gain	HOXB8 PRAC1 MIR10A HOXB9 HOXB13 HOXB-AS1 MIR3185 MIR196A1 HOXB7 HOXB-AS3 HOXB2 LOC105371809 HOXB5 HOXB6 HOXB1 PRAC2 HOXB3 HOXB4
dgv369n27	Chr.17:48543040 - 48621348 on Build GRCh38	Loss	HOXB8 HOXB7 HOXB-AS3 MIR10A HOXB9 HOXB2 HOXB5 HOXB6 HOXB-AS1 HOXB3 HOXB4

More Information

• Set Membership: Intragenic, Exonic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

helix-turn-helix transcription factor, homeodomain transcription factor, DNA-binding transcription factor, gene-specific transcriptional regulator

Gene Ontology Categories:

Process(es)

transcription from RNA polymerase II promoter
anatomical structure morphogenesis
anterior/posterior pattern specification
endothelial cell differentiation
positive regulation of transcription from RNA polymerase II promoter
embryonic skeletal system morphogenesis

Function(s)

RNA polymerase II distal enhancer sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
protein binding