Hs01243975_cn

• Gene Symbol: MAPK9
• Assay Reference Genome Location: Chr.5:180247904 on build GRCh38
• Cytoband: 5q35.3

Target Gene Details

• Entrez Gene ID: 5601
• Gene Name: mitogen-activated protein kinase 9
• Gene Aliases: JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK
• Location: Chr.5:180233594-180292071 on Build GRCh38
• Assay Gene Location: Overlaps Intron 8 - Exon 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MAPK9	NM_001135044.1			NP_001128516.1
	NM_001308244.1			NP_001295173.1
	NM_002752.4			NP_002743.3
	NM_139068.2			NP_620707.1
	NM_139069.2			NP_620708.1
	NM_139070.2			NP_620709.1
	XM_005265940.4			XP_005265997.1
	XM_006714891.2			XP_006714954.1
	XM_017009638.1			XP_016865127.1
	XM_017009639.1			XP_016865128.1
	XM_017009640.1			XP_016865129.1
	XM_017009641.1			XP_016865130.1
	XM_017009642.1			XP_016865131.1
	XM_017009643.1			XP_016865132.1
	AB451302.1
	AB451355.1
	AB451433.1
	AK289638.1
	BC032539.1			AAH32539.1
	CR536580.1			CAG38817.1
	EU927388.1
	HM036706.1
	HM036707.1
	HM036708.1
	HM036709.1
	L31951.1			AAA56831.1
	U09759.1			AAA74740.1
	U34821.1			AAC50606.1
	U35002.1			AAC50608.1
	U35003.1			AAC50609.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2759398	Chr.5:180107477 - 180302944 on Build GRCh38	Gain	RASGEF1C MAPK9 GFPT2
nsv1033706	Chr.5:179975769 - 180379356 on Build GRCh38	Gain	RASGEF1C MAPK9 GFPT2 MIR340 RNF130

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

release of cytochrome c from mitochondria
positive regulation of protein phosphorylation
protein phosphorylation
protein targeting to mitochondrion
activation of cysteine-type endopeptidase activity involved in apoptotic process
response to stress
JNK cascade
JUN phosphorylation
central nervous system development
response to mechanical stimulus
response to toxic substance
positive regulation of gene expression
positive regulation of macrophage derived foam cell differentiation
positive regulation of cell morphogenesis involved in differentiation
response to amine
neuron projection development
positive regulation of prostaglandin biosynthetic process
regulation of protein ubiquitination
positive regulation of prostaglandin secretion
positive regulation of chemokine production
cellular response to UV
Fc-epsilon receptor signaling pathway
response to drug
regulation of circadian rhythm
positive regulation of nitric oxide biosynthetic process
positive regulation of transcription, DNA-templated
regulation of JNK cascade
response to cadmium ion
rhythmic process
regulation of sequence-specific DNA binding transcription factor activity
positive regulation of nitric-oxide synthase biosynthetic process
cellular response to lipopolysaccharide
cellular response to interleukin-1
cellular response to tumor necrosis factor
cellular response to growth factor stimulus
positive regulation of podosome assembly
positive regulation of apoptotic signaling pathway

Function(s)

JUN kinase activity
protein binding
ATP binding
transcription factor binding
cysteine-type endopeptidase activator activity involved in apoptotic process
mitogen-activated protein kinase kinase kinase binding