Hs01245366_cn

• Gene Symbol: INPPL1
• Assay Reference Genome Location: Chr.11:72234592 on build GRCh38
• Cytoband: 11q13.4

Target Gene Details

• Entrez Gene ID: 3636
• Gene Name: inositol polyphosphate phosphatase like 1
• Gene Aliases: OPSMD, SHIP2
• Location: Chr.11:72223861-72239147 on Build GRCh38
• Assay Gene Location: Overlaps Exon 23 - Intron 23

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
INPPL1	NM_001567.3			NP_001558.3
	XM_005273978.3			XP_005274035.1
	XM_005273979.4			XP_005274036.1
	XM_011544999.2			XP_011543301.1
	XM_011545000.2			XP_011543302.1
	XM_017017673.1			XP_016873162.1
	BC140853.1
	L36818.1			AAA96658.1
	Y14385.1			CAA74743.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv951038	Chr.11:72226157 - 72253456 on Build GRCh38	Deletion	LOC220077 INPPL1 PHOX2A
nsv555405	Chr.11:72233623 - 72241301 on Build GRCh38	Loss	INPPL1 PHOX2A
nsv555404	Chr.11:72233198 - 72238908 on Build GRCh38	Gain+Loss	INPPL1

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

endochondral ossification
immune system process
glucose metabolic process
phosphatidylinositol biosynthetic process
endocytosis
actin filament organization
cell adhesion
negative regulation of cell proliferation
post-embryonic development
negative regulation of gene expression
response to insulin
inositol phosphate metabolic process
phosphatidylinositol dephosphorylation
ruffle assembly

Function(s)

actin binding
protein binding
SH3 domain binding
phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity
SH2 domain binding
inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity