Hs01263697_cn

• Gene Symbol: ANAPC1
• Assay Reference Genome Location: Chr.2:111884187 on build GRCh38
• Cytoband: 2q13

Target Gene Details

• Entrez Gene ID: 64682
• Gene Name: anaphase promoting complex subunit 1
• Gene Aliases: APC1, MCPR, TSG24
• Location: Chr.2:111766147-111884196 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ANAPC1	NM_022662.3			NP_073153.1
	XM_011511633.2			XP_011509935.1
	XM_011511634.2			XP_011509936.1
	XM_011511636.2			XP_011509938.1
	XM_011511637.2			XP_011509939.1
	XM_017004710.1			XP_016860199.1
	XM_017004711.1			XP_016860200.1
	XM_017004712.1			XP_016860201.1
	XM_017004713.1			XP_016860202.1
	XM_017004714.1			XP_016860203.1
	XM_017004715.1			XP_016860204.1
	AJ278357.1			CAC19484.1
	BX282336.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv582699	Chr.2:110763166 - 112172487 on Build GRCh38	Loss	LOC400997 ACOXL MIR4435-2HG PAFAH1B1P2 MIR4771-2 BCL2L11 TMEM87B MERTK FBLN7 ANAPC1 MIR4435-2
nsv521956	Chr.2:110634682 - 112341235 on Build GRCh38	Loss	ZC3H8 LOC400997 ACOXL BUB1 SNORD132 MIR4435-2HG MIR4771-2 BCL2L11 MERTK FBLN7 ANAPC1 MIR4435-2 PAFAH1B1P2 TMEM87B ZC3H6
nsv834333	Chr.2:111732634 - 111900770 on Build GRCh38	Gain	MIR4771-2 MERTK ANAPC1
nsv428402	Chr.2:111142206 - 111905020 on Build GRCh38	Loss	MIR4435-2HG PAFAH1B1P2 MIR4771-2 BCL2L11 MERTK ANAPC1 MIR4435-2
dgv4047n100	Chr.2:110308696 - 112358403 on Build GRCh38	Loss	ZC3H8 LOC400997 RGPD6 ACOXL BUB1 SNORD132 LINC01106 MIR4435-2HG MIR4771-2 LOC105375809 BCL2L11 MERTK FBLN7 ANAPC1 MIR4435-2 LOC100288570 PAFAH1B1P2 TMEM87B ZC3H6 LOC105373553 LIMS4

More Information

Additional Information:

• Set Membership: Intragenic, Non-exonic, DGV Variation, Validated

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

mitotic nuclear division
anaphase-promoting complex-dependent catabolic process
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
cell division
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
protein K11-linked ubiquitination