Hs01269544_cn

• Gene Symbol: NELFB
• Assay Reference Genome Location: Chr.9:137256023 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 25920
• Gene Name: negative elongation factor complex member B
• Gene Aliases: COBRA1, NELF-B
• Location: Chr.9:137255300-137273548 on Build GRCh38
• Assay Gene Location: Overlaps Exon 2 - Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NELFB	NM_015456.4			NP_056271.3
	AF464935.1			AAL69965.1
	AK091056.1
	BC011892.1			AAH11892.1
	DA210427.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv13009n54	Chr.9:137173890 - 137327859 on Build GRCh38	Loss	ANAPC2 TUBB4B NRARP C9orf173-AS1 SSNA1 RNF224 TPRN RNF208 FAM166A CYSRT1 EXD3 TMEM203 STPG3 TOR4A SLC34A3 NELFB NDOR1
dgv13011n54	Chr.9:137223996 - 137338927 on Build GRCh38	Loss	FAM166A TUBB4B CYSRT1 EXD3 NRARP C9orf173-AS1 STPG3 TOR4A SLC34A3 RNF224 NELFB
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	CLIC3 TUBB4B MIR3621 C9orf173-AS1 SSNA1 NOXA1 CCDC183 LCN12 MAMDC4 NSMF ENTPD2 NDOR1 NPDC1 ANAPC2 MIR7114 LRRC26 PRR31 ABCA2 SAPCD2 RNF208 EXD3 TMEM203 LOC101930307 C9orf142 TOR4A RABL6 NELFB MAN1B1-AS1 LCNL1 NRARP CCDC183-AS1 RNF224 PNPLA7 EDF1 FBXW5 C8G UAP1L1 TPRN FAM166A MIR4479 PTGDS MIR4292 C9orf172 ENTPD8 CYSRT1 DPP7 STPG3 TMEM210 MAN1B1 FUT7 TRAF2 SLC34A3 PHPT1 GRIN1 C9orf139
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	ANAPC2 TUBB4B MIR3621 NRARP C9orf173-AS1 SSNA1 LRRC26 RNF224 TPRN RNF208 FAM166A CYSRT1 EXD3 TMEM203 STPG3 TMEM210 TOR4A SLC34A3 GRIN1 NELFB NDOR1
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	ANAPC2 TUBB4B MIR3621 NRARP C9orf173-AS1 SSNA1 LRRC26 NOXA1 ENTPD8 RNF224 TPRN RNF208 FAM166A CYSRT1 EXD3 TMEM203 STPG3 TMEM210 TOR4A SLC34A3 GRIN1 NELFB NDOR1
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	CLIC3 TUBB4B MIR3621 C9orf173-AS1 SSNA1 CCDC183 AGPAT2 SNORA17B SNHG7 SNORA17A LCN12 MAMDC4 LCN15 ENTPD2 NDOR1 NPDC1 ANAPC2 LCN6 FAM69B LOC100128593 LRRC26 PRR31 ABCA2 SAPCD2 RNF208 LINC01451 EXD3 TMEM203 LOC101930307 C9orf142 TOR4A LCN8 RABL6 NELFB MAN1B1-AS1 LCNL1 HSPC324 NRARP MIR6722 MIR126 CCDC183-AS1 RNF224 EDF1 FBXW5 C8G UAP1L1 TPRN LCN10 FAM166A MIR4479 PTGDS MIR4292 C9orf172 CYSRT1 DPP7 STPG3 TMEM141 TMEM210 MAN1B1 FUT7 TRAF2 SLC34A3 EGFL7 PHPT1 GRIN1 C9orf139

More Information

Additional Information:

For this assay, SNP(s) [rs139208158] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

transcription from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
negative regulation of transcription elongation from RNA polymerase II promoter
positive regulation of viral transcription

Function(s)

protein binding