Hs01269562_cn

• Gene Symbol: DNASE1
• Assay Reference Genome Location: Chr.16:3657921 on build GRCh38
• Cytoband: 16p13.3

Target Gene Details

• Entrez Gene ID: 1773
• Gene Name: deoxyribonuclease I
• Gene Aliases: DNL1, DRNI
• Location: Chr.16:3611705-3665472 on Build GRCh38
• Assay Gene Location: Within Exon 14

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DNASE1	NM_005223.3			NP_005214.2
	XM_005255148.3			XP_005255205.1
	XM_006720854.3			XP_006720917.1
	XM_011522393.2			XP_011520695.1
	XM_017022992.1			XP_016878481.1
	XM_017022993.1			XP_016878482.1
	XM_017022994.1			XP_016878483.1
	XM_017022995.1			XP_016878484.1
	XM_017022996.1			XP_016878485.1
	XM_017022997.1			XP_016878486.1
	XM_017022998.1			XP_016878487.1
	XM_017022999.1			XP_016878488.1
	XM_017023000.1			XP_016878489.1
	XM_017023001.1			XP_016878490.1
	XM_017023002.1			XP_016878491.1
	XM_017023003.1			XP_016878492.1
	XM_017023004.1			XP_016878493.1
	XM_017023005.1			XP_016878494.1
	XM_017023006.1			XP_016878495.1
	XM_017023007.1	10	1811	XP_016878496.1
	AB188151.1
	AB188152.1
	AI378682.1
	AJ298844.1			CAC12813.1
	AK300914.1
	BC029437.1			AAH29437.1
	BX648257.1	6	922
	M55983.1			AAA63170.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833128	Chr.16:3525122 - 3690497 on Build GRCh38	Loss	SLX4 NLRC3 LOC101929732 DNASE1 TRAP1 CLUAP1
esv2761892	Chr.16:3651576 - 3669343 on Build GRCh38	Loss	DNASE1 TRAP1
nsv518509	Chr.16:3583656 - 3688960 on Build GRCh38	Gain	SLX4 DNASE1 TRAP1
nsv525301	Chr.16:3657746 - 3668847 on Build GRCh38	Loss	DNASE1 TRAP1
esv3637673	Chr.16:3653616 - 3669650 on Build GRCh38	Loss	DNASE1 TRAP1
nsv1051657	Chr.16:3644759 - 3788297 on Build GRCh38	Gain	CREBBP DNASE1 TRAP1
nsv457359	Chr.16:3655014 - 3668847 on Build GRCh38	Loss	DNASE1 TRAP1
esv2659167	Chr.16:3653585 - 3669799 on Build GRCh38	Deletion	DNASE1 TRAP1

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

DNA catabolic process
apoptotic process
nucleic acid phosphodiester bond hydrolysis

Function(s)

actin binding
deoxyribonuclease I activity
protein binding