Hs01278909_cn

• Gene Symbol: IDH3B
• Assay Reference Genome Location: Chr.20:2663566 on build GRCh38
• Cytoband: 20p13

Target Gene Details

• Entrez Gene ID: 3420
• Gene Name: isocitrate dehydrogenase 3 (NAD(+)) beta
• Gene Aliases: RP46
• Location: Chr.20:2658390-2664223 on Build GRCh38
• Assay Gene Location: Overlaps Intron 3 - Exon 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
IDH3B	NM_001258384.2			NP_001245313.1
	NM_006899.4			NP_008830.2
	NM_174855.3			NP_777280.1
	NR_136344.1
	XM_005260716.1			XP_005260773.1
	AK001905.1			BAA91971.1
	AK300485.1
	AK309488.1
	AK315641.1
	BC001960.1			AAH01960.1
	BP872064.1
	BX647393.1
	HY131986.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1057464	Chr.20:2650623 - 2989686 on Build GRCh38	Gain	C20orf141 SNORD57 SNORD110 NOP56 SNORD86 PCED1A VPS16 TMEM239 PTPRA SNORA51 SNORD56 CPXM1 MIR1292 EBF4 IDH3B
nsv470535	Chr.20:1948896 - 2780594 on Build GRCh38	Gain	TMC2 SNORD57 SNORD110 ZNF343 NOP56 SNORD86 LOC727993 SNORA51 SNORD56 STK35 TGM3 PDYN LOC388780 MIR1292 SNORD119 EBF4 SNRPB IDH3B TGM6
esv3644998	Chr.20:2148722 - 2690694 on Build GRCh38	Gain	TMC2 SNORD57 SNORD110 ZNF343 NOP56 SNORD86 SNORA51 SNORD56 TGM3 LOC388780 MIR1292 SNORD119 SNRPB IDH3B TGM6
nsv458852	Chr.20:2657933 - 2704278 on Build GRCh38	Loss	NOP56 EBF4 IDH3B

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

dehydrogenase

Gene Ontology Categories:

Process(es)

tricarboxylic acid cycle
isocitrate metabolic process
2-oxoglutarate metabolic process
NADH metabolic process

Function(s)

magnesium ion binding
isocitrate dehydrogenase (NAD+) activity
electron carrier activity
NAD binding