Hs01291377_cn

• Gene Symbol: TRADD
• Assay Reference Genome Location: Chr.16:67155993 on build GRCh38
• Cytoband: 16q22.1

Target Gene Details

• Entrez Gene ID: 8717
• Gene Name: TNFRSF1A associated via death domain
• Gene Aliases: Hs.89862
• Location: Chr.16:67154185-67159909 on Build GRCh38
• Assay Gene Location: Within Exon 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TRADD	NM_001323552.1			NP_001310481.1
	NM_003789.3			NP_003780.1
	XM_005256213.3	3	410	XP_005256270.1
	XM_017023815.1			XP_016879304.1
	AK090673.1	1	257
	AK301593.1	3	428
	AK315654.1
	BC004491.2			AAH04491.1
	BG717460.1
	BT006934.1			AAP35580.1
	DA353575.1
	L41690.1			AAA98482.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv522852	Chr.16:67153308 - 68071571 on Build GRCh38	Gain	PLEKHG4 PSMB10 SLC12A4 LCAT ACD PARD6A CENPT E2F4 LRRC29 TRADD C16orf86 ELMO3 EDC4 DPEP2 LOC100505942 FHOD1 HSD11B2 NOL3 GFOD2 NUTF2 HSF4 THAP11 KIAA0895L CARMIL2 ATP6V0D1 EXOC3L1 TSNAXIP1 PSKH1 DPEP3 ZDHHC1 TMEM208 DDX28 FBXL8 NRN1L LRRC36 LOC100131303 TPPP3 LOC107984813 KCTD19 CTRL DUS2 AGRP LOC105369155 ENKD1 MIR328 FAM65A SLC9A5 RANBP10 CTCF
nsv827707	Chr.16:67148355 - 67289296 on Build GRCh38	Loss	PLEKHG4 ELMO3 B3GNT9 C16orf70 EXOC3L1 FHOD1 NOL3 E2F4 LOC105369155 MIR328 TMEM208 LRRC29 TRADD HSF4 SLC9A5 FBXL8 KIAA0895L
nsv952044	Chr.16:67141198 - 67244397 on Build GRCh38	Deletion	ELMO3 B3GNT9 C16orf70 EXOC3L1 FHOD1 NOL3 E2F4 LOC105369155 MIR328 TMEM208 LRRC29 TRADD HSF4 FBXL8 KIAA0895L
nsv524363	Chr.16:67136529 - 68071571 on Build GRCh38	Loss	PLEKHG4 PSMB10 SLC12A4 LCAT ACD PARD6A CENPT E2F4 LRRC29 TRADD C16orf86 ELMO3 EDC4 DPEP2 LOC100505942 FHOD1 HSD11B2 NOL3 GFOD2 NUTF2 HSF4 THAP11 KIAA0895L CARMIL2 B3GNT9 ATP6V0D1 EXOC3L1 TSNAXIP1 PSKH1 DPEP3 ZDHHC1 TMEM208 DDX28 FBXL8 NRN1L LRRC36 LOC100131303 TPPP3 C16orf70 LOC107984813 KCTD19 CTRL DUS2 AGRP LOC105369155 ENKD1 MIR328 FAM65A SLC9A5 RANBP10 CTCF

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
signal transduction
I-kappaB kinase/NF-kappaB signaling
extrinsic apoptotic signaling pathway via death domain receptors
regulation of tumor necrosis factor-mediated signaling pathway
regulation of necrotic cell death
tumor necrosis factor-mediated signaling pathway
positive regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of NF-kappaB transcription factor activity
protein heterooligomerization
positive regulation of hair follicle development
death-inducing signaling complex assembly
extrinsic apoptotic signaling pathway
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

Function(s)

signal transducer activity
tumor necrosis factor receptor binding
protein binding
kinase binding
protein complex binding
identical protein binding
binding, bridging
death domain binding