Hs01295737_cn

• Gene Symbol: IQGAP3
• Assay Reference Genome Location: Chr.1:156526576 on build GRCh38
• Cytoband: 1q22

Target Gene Details

• Entrez Gene ID: 128239
• Gene Name: IQ motif containing GTPase activating protein 3
• Gene Aliases: -
• Location: Chr.1:156525405-156572604 on Build GRCh38
• Assay Gene Location: Overlaps Intron 39 - Exon 40

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
IQGAP3	NM_178229.4			NP_839943.2
	XM_011509198.2			XP_011507500.1
	XM_011509200.2			XP_011507502.1
	XM_011509201.2			XP_011507503.1
	XM_017000317.1			XP_016855806.1
	XM_017000318.1			XP_016855807.1
	AB105103.1			BAC78211.1
	AK122653.1			BAC85501.1
	AY253300.1			AAP06954.1
	BC131536.1
	BM910515.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv952215	Chr.1:156524609 - 156527308 on Build GRCh38	Deletion	IQGAP3

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

G-protein modulator, protein-binding activity modulator, GTPase-activating protein

Gene Ontology Categories:

Process(es)

G1/S transition of mitotic cell cycle
activation of MAPK activity
Ras protein signal transduction
regulation of cell size
positive regulation of gene expression
negative regulation of gene expression
positive regulation of mammary gland epithelial cell proliferation
regulation of GTPase activity
ERK1 and ERK2 cascade
cellular response to organic substance

Function(s)

calmodulin binding
Rho GTPase binding
myosin VI light chain binding