Hs01307764_cn

• Gene Symbol: LOC105371998
• Assay Reference Genome Location: Chr.18:12447510 on build GRCh38
• Cytoband: 18p11.21

Target Gene Details

• Entrez Gene ID: 105371998
• Gene Name: uncharacterized LOC105371998
• Gene Aliases: -
• Location: Chr.18:12432774-12447798 on Build GRCh38
• Assay Gene Location: Overlaps Intron 5 - Exon 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LOC105371998	NR_136514.1
	AK090999.1	1	2260
	AK128548.1	1	4215
	BU620199.1

Target Gene Details

• Entrez Gene ID: 56907
• Gene Name: spire type actin nucleation factor 1
• Gene Aliases: Spir-1
• Location: Chr.18:12446512-12658102 on Build GRCh38
• Assay Gene Location: Within Exon 21

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SPIRE1	NM_001128626.1	17	4446	NP_001122098.1
	NM_001128627.1	16	4102	NP_001122099.1
	NM_020148.2	16	4404	NP_064533.3
	XM_005258122.4	17	4761	XP_005258179.1
	XM_011525701.1	18	4809	XP_011524003.1
	XM_011525702.1	18	4321	XP_011524004.1
	AB032961.2	17	4498
	AJ277587.1	14	3991	CAB96370.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1060808	Chr.18:12302793 - 12514418 on Build GRCh38	Gain	AFG3L2 SPIRE1 PRELID3A LOC105371998 TUBB6
nsv576496	Chr.18:12247873 - 12490503 on Build GRCh38	Gain	AFG3L2 CIDEA SPIRE1 PRELID3A LOC105371998 TUBB6
nsv1063125	Chr.18:12046893 - 12918252 on Build GRCh38	Loss	LOC100996324 AFG3L2 CIDEA SPIRE1 PRELID3A LOC105371998 TUBB6 CEP76 C18orf61 PSMG2 LOC100996333 ANKRD62 PTPN2
esv2758714	Chr.18:12240682 - 12499526 on Build GRCh38	Loss	AFG3L2 CIDEA SPIRE1 PRELID3A LOC105371998 TUBB6

More Information

• Set Membership: Intragenic, Exonic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

actin or actin-binding cytoskeletal protein

Gene Ontology Categories:

Process(es)

protein transport
vesicle-mediated transport
actin cytoskeleton organization
cleavage furrow formation
polar body extrusion after meiotic divisions
actin nucleation
intracellular transport
establishment of meiotic spindle localization
formin-nucleated actin cable assembly

Function(s)

actin binding