Hs01318522_cn

• Gene Symbol: TRIM28
• Assay Reference Genome Location: Chr.19:58549246 on build GRCh38
• Cytoband: 19q13.43

Target Gene Details

• Entrez Gene ID: 10155
• Gene Name: tripartite motif containing 28
• Gene Aliases: KAP1, PPP1R157, RNF96, TF1B, TIF1B
• Location: Chr.19:58544469-58550715 on Build GRCh38
• Assay Gene Location: Overlaps Exon 12 - Intron 12

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TRIM28	NM_005762.2			NP_005753.1
	AK131063.1
	AK225760.1
	AK313478.1
	BC004978.1			AAH04978.1
	BC007390.2			AAH07390.2
	BC052986.2			AAH52986.1
	U31657.1			AAA74954.1
	U78773.1			AAB37341.1
	U95040.1			AAB51517.1
	X97548.1			CAA66150.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv515731	Chr.19:58320453 - 58576112 on Build GRCh38	Gain+Loss	CHMP2A UBE2M MIR6807 MZF1 TRIM28 RPS5 CENPBD1P1 MZF1-AS1 MIR6806 ZNF837 LOC100506634 MIR4754 LOC100419840 ZNF324 ZNF497 SLC27A5 LOC105372483 ZSCAN22 ZBTB45 ZNF584 A1BG ZNF446 RNF225 A1BG-AS1 ZNF132 ZNF324B
nsv1057206	Chr.19:58546716 - 58586475 on Build GRCh38	Gain	CENPBD1P1 MZF1-AS1 CHMP2A UBE2M MIR6807 MZF1 TRIM28
dgv3687n100	Chr.19:58473466 - 58586475 on Build GRCh38	Gain	CENPBD1P1 ZNF324 ZNF446 SLC27A5 MZF1-AS1 ZBTB45 CHMP2A UBE2M MIR6807 MZF1 TRIM28
nsv952156	Chr.19:58466134 - 58600733 on Build GRCh38	Deletion	CENPBD1P1 ZNF324 ZNF446 SLC27A5 MZF1-AS1 ZBTB45 CHMP2A UBE2M MIR6807 MZF1 TRIM28
nsv1160670	Chr.19:58433008 - 58586487 on Build GRCh38	Deletion	ZNF324 SLC27A5 ZBTB45 CHMP2A UBE2M MIR6807 MZF1 TRIM28 CENPBD1P1 ZNF446 MZF1-AS1 ZNF132 ZNF324B
nsv828657	Chr.19:58483484 - 58585740 on Build GRCh38	Gain	CENPBD1P1 ZNF446 SLC27A5 MZF1-AS1 ZBTB45 CHMP2A UBE2M MIR6807 MZF1 TRIM28
dgv3688n100	Chr.19:58506055 - 58586475 on Build GRCh38	Gain	CENPBD1P1 SLC27A5 MZF1-AS1 ZBTB45 CHMP2A UBE2M MIR6807 MZF1 TRIM28
nsv1057077	Chr.19:58411953 - 58586475 on Build GRCh38	Gain	ZNF324 SLC27A5 ZBTB45 CHMP2A UBE2M ZNF584 MIR6807 MZF1 TRIM28 CENPBD1P1 ZNF446 MZF1-AS1 ZNF132 ZNF324B

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
epithelial to mesenchymal transition
DNA repair
transcription initiation from RNA polymerase II promoter
Ras protein signal transduction
embryo implantation
protein ubiquitination
covalent chromatin modification
protein sumoylation
positive regulation of transcription factor import into nucleus
DNA methylation involved in embryo development
innate immune response
positive regulation of DNA repair
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
protein autophosphorylation
protein oligomerization
convergent extension involved in axis elongation
embryonic placenta morphogenesis
positive regulation of methylation-dependent chromatin silencing
negative regulation of DNA demethylation
negative regulation of viral release from host cell
regulation of genetic imprinting

Function(s)

RNA polymerase II transcription coactivator activity
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
protein kinase activity
ubiquitin-protein transferase activity
protein binding
zinc ion binding
ligase activity
ubiquitin protein ligase binding
Krueppel-associated box domain binding
sequence-specific DNA binding
poly(A) RNA binding
chromo shadow domain binding
promoter-specific chromatin binding