Hs01356036_cn

• Gene Symbol: PTPN23
• Assay Reference Genome Location: Chr.3:47404703 on build GRCh38
• Cytoband: 3p21.31

Target Gene Details

• Entrez Gene ID: 25930
• Gene Name: protein tyrosine phosphatase, non-receptor type 23
• Gene Aliases: HD-PTP, HDPTP, PTP-TD14
• Location: Chr.3:47380982-47413441 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PTPN23	NM_001304482.1			NP_001291411.1
	NM_015466.3	3	326	NP_056281.1
	XM_005265031.2	3	307	XP_005265088.2
	AB025194.1	3	274	BAB19280.1
	AB040904.2	3	326
	AF290614.1	3	272	AAK28025.1
	AK055157.1	3	297
	AK289502.1	3	275
	AK295877.1	3	246
	AK295888.1	2	219
	AK299906.1
	BC089042.1	3	244	AAH89042.1
	DA093189.1	3	307

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv428417	Chr.3:46638962 - 47778557 on Build GRCh38	Loss	NRADDP CCDC12 TMIE KIF9-AS1 SMARCC1 KIF9 PTPN23 PRSS43 SNORD13P3 KLHL18 NBEAL2 CSPG5 SCAP PRSS45 PRSS42 MYL3 PRSS50 ALS2CL PTH1R PRSS46 ELP6 SETD2

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

membrane traffic protein

Gene Ontology Categories:

Process(es)

negative regulation of epithelial cell migration
protein transport
peptidyl-tyrosine dephosphorylation
ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
cilium morphogenesis
positive regulation of homophilic cell adhesion
positive regulation of adherens junction organization
positive regulation of early endosome to late endosome transport

Function(s)

protein tyrosine phosphatase activity
protein binding
protein kinase binding