Hs01381380_cn

• Gene Symbol: CHRNA2
• Assay Reference Genome Location: Chr.8:27471081 on build GRCh38
• Cytoband: 8p21.2

Target Gene Details

• Entrez Gene ID: 1135
• Gene Name: cholinergic receptor nicotinic alpha 2 subunit
• Gene Aliases: -
• Location: Chr.8:27459761-27479296 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CHRNA2	NM_000742.3	2	587	NP_000733.2
	NM_001282455.1	2	587	NP_001269384.1
	XM_005273397.2	2	511	XP_005273454.1
	XM_006716282.1	3	498	XP_006716345.1
	XM_011544388.1	3	589	XP_011542690.1
	XM_011544389.1	2	587	XP_011542691.1
	XM_017013003.1	2	564	XP_016868492.1
	XM_017013004.1	3	498	XP_016868493.1
	AK296348.1	2	142
	AK314787.1	2	505
	BC153866.1
	CD013901.1	1	103
	DA096824.1
	DA407151.1
	U62431.1	2	532	AAB40109.1
	Y16281.1			CAA76154.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv831275	Chr.8:27470773 - 27624088 on Build GRCh38	Loss	CHRNA2 MIR6843 EPHX2 CLU
nsv1020582	Chr.8:27452251 - 27549327 on Build GRCh38	Gain	CHRNA2 EPHX2 PTK2B

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

ligand-gated ion channel

Gene Ontology Categories:

Process(es)

ion transport
signal transduction
synaptic transmission, cholinergic
neuromuscular synaptic transmission
response to nicotine
protein heterooligomerization
cation transmembrane transport

Function(s)

acetylcholine-activated cation-selective channel activity
drug binding
ligand-gated ion channel activity
acetylcholine receptor activity
acetylcholine binding