Hs01418013_cn

• Gene Symbol: TAOK3
• Assay Reference Genome Location: Chr.12:118160187 on build GRCh38
• Cytoband: 12q24.23

Target Gene Details

• Entrez Gene ID: 51347
• Gene Name: TAO kinase 3
• Gene Aliases: DPK, JIK, MAP3K18
• Location: Chr.12:118149801-118372950 on Build GRCh38
• Assay Gene Location: Overlaps Intron 22 - Exon 22

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TAOK3	NM_016281.3			NP_057365.3
	XM_005253897.1			XP_005253954.1
	XM_005253898.1			XP_005253955.1
	XM_006719445.2			XP_006719508.1
	XM_011538437.1			XP_011536739.1
	XM_011538439.1			XP_011536741.1
	XM_017019408.1			XP_016874897.1
	XM_017019409.1			XP_016874898.1
	XM_017019410.1			XP_016874899.1
	XM_017019411.1			XP_016874900.1
	XM_017019412.1			XP_016874901.1
	XM_017019413.1			XP_016874902.1
	AF135158.1			AAG09131.1
	AF161373.1			AAF28933.1
	AF179867.1			AAF14559.1
	AF181985.1			AAF25817.1
	AF263311.1			AAG38501.1
	AF328731.1			AAN09723.1
	AK056370.1
	AK289558.1
	AL833460.1
	AL833731.1			CAH56239.1
	BC002756.2			AAH02756.1
	BT007185.1			AAP35849.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3581916	Chr.12:117356518 - 118228514 on Build GRCh38	Gain	PEBP1 KSR2 TAOK3 VSIG10 RFC5 WSB2 NOS1

More Information

Additional Information:

For this assay, SNP(s) [rs79932870] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

MAPK cascade
DNA repair
protein phosphorylation
negative regulation of protein kinase activity
cellular response to DNA damage stimulus
mitotic G2 DNA damage checkpoint
positive regulation of stress-activated MAPK cascade
positive regulation of JUN kinase activity
negative regulation of JNK cascade
positive regulation of JNK cascade
protein autophosphorylation

Function(s)

protein serine/threonine kinase activity
receptor signaling protein serine/threonine kinase activity
protein kinase inhibitor activity
protein binding
ATP binding
transferase activity