Hs01421627_cn

• Gene Symbol: PI4KB
• Assay Reference Genome Location: Chr.1:151291805 on build GRCh38
• Cytoband: 1q21.3

Target Gene Details

• Entrez Gene ID: 5298
• Gene Name: phosphatidylinositol 4-kinase beta
• Gene Aliases: NPIK, PI4K-BETA, PI4K92, PI4KBETA, PI4KIIIBETA, PIK4CB
• Location: Chr.1:151291797-151327715 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 15

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PI4KB	NM_001198773.1			NP_001185702.1
	NM_001198774.1			NP_001185703.1
	NM_001198775.1			NP_001185704.1
	NM_002651.2			NP_002642.1
	XM_005245264.3			XP_005245321.1
	XM_011509634.1			XP_011507936.1
	XM_011509635.1			XP_011507937.1
	XM_011509636.2			XP_011507938.1
	XM_011509637.2			XP_011507939.1
	XM_011509638.1			XP_011507940.1
	XM_017001486.1			XP_016856975.1
	XM_017001487.1			XP_016856976.1
	XM_017001488.1			XP_016856977.1
	XM_017001489.1			XP_016856978.1
	XM_017001490.1			XP_016856979.1
	XM_017001491.1			XP_016856980.1
	XM_017001492.1			XP_016856981.1

Target Gene Details

• Entrez Gene ID: 57592
• Gene Name: zinc finger protein 687
• Gene Aliases: PDB6
• Location: Chr.1:151281555-151291905 on Build GRCh38
• Assay Gene Location: Within Exon 12

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ZNF687	NM_001304763.1	10	5280	NP_001291692.1
	NM_001304764.1	9	4481	NP_001291693.1
	NM_020832.2	9	4411	NP_065883.1
	XM_005245366.3	9	4849	XP_005245423.1
	XM_011509811.2	8	4281	XP_011508113.1
	XM_011509812.2	10	4728	XP_011508114.1
	XM_011509813.2	9	4612	XP_011508115.1
	AB037862.1	10	5280
	AK023105.1	8	3179	BAB14406.1
	BC032463.1	9	4408	AAH32463.1
	CR749307.1	9	4482	CAH18162.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv522840	Chr.1:150961247 - 151375270 on Build GRCh38	Gain	BNIPL TNFAIP8L2-SCNM1 C1orf56 PIP5K1A SCNM1 ZNF687 CERS2 FAM63A GBAT2 GABPB2 TNFAIP8L2 LYSMD1 TMOD4 SELENBP1 VPS72 PI4KB PRUNE1 SETDB1 RFX5 CDC42SE1 ANXA9 LOC100507670 MLLT11 SEMA6C PSMD4
esv34461	Chr.1:151268066 - 151439159 on Build GRCh38	Gain	PI4KB RFX5 GBAT2 POGZ LOC100507670 SELENBP1 PSMB4 ZNF687
dgv2n68	Chr.1:151136983 - 151309302 on Build GRCh38	Loss	LYSMD1 PI4KB TMOD4 TNFAIP8L2-SCNM1 LOC100507670 PIP5K1A SCNM1 TNFAIP8L2 SEMA6C VPS72 ZNF687 PSMD4

More Information

• Set Membership: Intragenic, Exonic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

kinase

Gene Ontology Categories:

Process(es)

phosphatidylinositol biosynthetic process
receptor-mediated endocytosis
signal transduction
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling
transcription, DNA-templated
regulation of transcription, DNA-templated

Function(s)

1-phosphatidylinositol 4-kinase activity
protein binding
ATP binding
14-3-3 protein binding
DNA binding
metal ion binding