Hs01425464_cn

• Gene Symbol: CHRNA6
• Assay Reference Genome Location: Chr.8:42768494 on build GRCh38
• Cytoband: 8p11.21

Target Gene Details

• Entrez Gene ID: 8973
• Gene Name: cholinergic receptor nicotinic alpha 6 subunit
• Gene Aliases: CHNRA6
• Location: Chr.8:42752620-42768786 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CHRNA6	NM_001199279.1	1	293	NP_001186208.1
	NM_004198.3	1	293	NP_004189.1
	AK298798.1	1	117
	AK313521.1	1	139
	BC014456.1			AAH14456.1
	DC307404.1	1	295
	U62435.1	1	79	AAB40113.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv483102	Chr.8:42722031 - 42876093 on Build GRCh38	Loss	CHRNA6 RNF170 THAP1 CHRNB3

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

ligand-gated ion channel

Gene Ontology Categories:

Process(es)

transport
signal transduction
chemical synaptic transmission
synaptic transmission, cholinergic
neuromuscular synaptic transmission
regulation of dopamine secretion
response to nicotine
membrane depolarization
cation transmembrane transport

Function(s)

acetylcholine-activated cation-selective channel activity
ligand-gated ion channel activity
acetylcholine receptor activity
acetylcholine binding