Hs01440216_cn

• Gene Symbol: VDR
• Assay Reference Genome Location: Chr.12:47843191 on build GRCh38
• Cytoband: 12q13.11

Target Gene Details

• Entrez Gene ID: 7421
• Gene Name: vitamin D (1,25- dihydroxyvitamin D3) receptor
• Gene Aliases: NR1I1, PPP1R163
• Location: Chr.12:47841537-47905031 on Build GRCh38
• Assay Gene Location: Within Exon 11

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
VDR	NM_000376.2	10	2999	NP_000367.1
	NM_001017535.1	11	3121	NP_001017535.1
	NM_001017536.1	10	3390	NP_001017536.1
	AK024830.1	1	1123
	AK225844.1	10	2998
	BC060832.1	10	3362	AAH60832.1
	J03258.1	10	2954	AAA61273.1

More Information

Additional Information:

For this assay, SNP(s) [rs115591719] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, non-DGV Variation

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
cell morphogenesis
skeletal system development
transcription initiation from RNA polymerase II promoter
calcium ion transport
cellular calcium ion homeostasis
signal transduction
lactation
negative regulation of cell proliferation
positive regulation of gene expression
negative regulation of keratinocyte proliferation
positive regulation of vitamin D 24-hydroxylase activity
bile acid signaling pathway
steroid hormone mediated signaling pathway
positive regulation of keratinocyte differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
decidualization
intestinal absorption
positive regulation of apoptotic process involved in mammary gland involution
regulation of calcidiol 1-monooxygenase activity
mammary gland branching involved in pregnancy
vitamin D receptor signaling pathway

Function(s)

DNA binding
transcription factor activity, sequence-specific DNA binding
steroid hormone receptor activity
protein binding
zinc ion binding
calcitriol receptor activity
lithocholic acid receptor activity
sequence-specific DNA binding
retinoid X receptor binding
vitamin D response element binding
calcitriol binding
lithocholic acid binding