Hs01478189_cn

• Gene Symbol: FAN1
• Assay Reference Genome Location: Chr.15:30925912 on build GRCh38
• Cytoband: 15q13.3

Target Gene Details

• Entrez Gene ID: 22909
• Gene Name: FANCD2/FANCI-associated nuclease 1
• Gene Aliases: KIAA1018, KMIN, MTMR15, hFAN1
• Location: Chr.15:30903695-30943108 on Build GRCh38
• Assay Gene Location: Overlaps Exon 11 - Intron 11

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
FAN1	NM_014967.4			NP_055782.3
	XM_005254232.4			XP_005254289.1
	XM_005254234.4			XP_005254291.1
	XM_005254235.3			XP_005254292.1
	XM_011521370.2			XP_011519672.1
	XM_011521371.1			XP_011519673.1
	XM_017022012.1			XP_016877501.1
	XM_017022013.1			XP_016877502.1
	AB023235.2
	CR936727.1
	CR936734.1
	HM560957.1
	KJ535046.1

Target Gene Details

• Entrez Gene ID: 54893
• Gene Name: myotubularin related protein 10
• Gene Aliases: -
• Location: Chr.15:30919764-30991604 on Build GRCh38
• Assay Gene Location: Within Intron 17

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MTMR10	XM_011521737.2			XP_011520039.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv832951	Chr.15:30839036 - 31012266 on Build GRCh38	Loss	MTMR10 FAN1 TRPM1
nsv525795	Chr.15:30644082 - 31032328 on Build GRCh38	Gain	MTMR10 LOC101930434 FAN1 LOC107984025 LOC100288637 HERC2P10 TRPM1
esv3569376	Chr.15:30781533 - 30987140 on Build GRCh38	Gain	MTMR10 LOC101930434 FAN1 LOC107984025 HERC2P10
esv33507	Chr.15:30891121 - 31178820 on Build GRCh38	Loss	MIR211 MTMR10 FAN1 TRPM1
nsv521842	Chr.15:30848497 - 30980467 on Build GRCh38	Gain	MTMR10 FAN1
nsv1046874	Chr.15:30715930 - 31002451 on Build GRCh38	Gain	MTMR10 LOC101930434 FAN1 LOC107984025 LOC100288637 HERC2P10 TRPM1
esv3636036	Chr.15:30818302 - 31038636 on Build GRCh38	Gain	MTMR10 FAN1 HERC2P10 TRPM1
nsv832952	Chr.15:30912223 - 31041795 on Build GRCh38	Gain+Loss	MTMR10 FAN1 TRPM1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

phosphatase

Gene Ontology Categories:

Process(es)

double-strand break repair via homologous recombination
DNA repair
nucleotide-excision repair
nucleotide-excision repair, DNA incision
interstrand cross-link repair

Function(s)

magnesium ion binding
phosphodiesterase I activity
protein binding
5'-3' exonuclease activity
5'-flap endonuclease activity
ubiquitin binding
flap-structured DNA binding