Hs01479710_cn

• Gene Symbol: CERS2
• Assay Reference Genome Location: Chr.1:150967091 on build GRCh38
• Cytoband: 1q21.3

Target Gene Details

• Entrez Gene ID: 29956
• Gene Name: ceramide synthase 2
• Gene Aliases: L3, LASS2, SP260, TMSG1
• Location: Chr.1:150965173-150975003 on Build GRCh38
• Assay Gene Location: Overlaps Intron 10 - Exon 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CERS2	NM_022075.4			NP_071358.1
	NM_181746.3			NP_859530.1
	XM_011509451.2			XP_011507753.1
	XM_011509452.2			XP_011507754.1
	AF177338.2			AAG17982.2
	AF189062.4			AAF01058.4
	AK001105.1			BAA91505.1
	AK290989.1
	AY091458.1			AAM12028.1
	BC001357.2			AAH01357.2
	BC010032.2			AAH10032.1
	BQ219926.1
	BU543940.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv522317	Chr.1:150961247 - 151001686 on Build GRCh38	Loss	FAM63A CERS2 ANXA9 SETDB1
nsv952804	Chr.1:150964125 - 150976324 on Build GRCh38	Deletion	CERS2 SETDB1
nsv1008496	Chr.1:150873351 - 150998180 on Build GRCh38	Gain	FAM63A CERS2 ANXA9 SETDB1 ARNT

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

sphingolipid biosynthetic process
ceramide biosynthetic process
negative regulation of axon regeneration
negative regulation of Schwann cell migration
negative regulation of Schwann cell proliferation involved in axon regeneration

Function(s)

DNA binding
protein binding
sphingosine N-acyltransferase activity