Hs01494557_cn

• Gene Symbol: CASP2
• Assay Reference Genome Location: Chr.7:143305941 on build GRCh38
• Cytoband: 7q34

Target Gene Details

• Entrez Gene ID: 835
• Gene Name: caspase 2
• Gene Aliases: CASP-2, ICH1, NEDD-2, NEDD2, PPP1R57
• Location: Chr.7:143288215-143307696 on Build GRCh38
• Assay Gene Location: Within Exon 13

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CASP2	NM_001224.4	12	2285	NP_001215.1
	NM_032982.3	11	2470	NP_116764.2
	NM_032983.3	10	2252	NP_116765.2
	AB209640.1	5	5142	BAD92877.1
	BC002427.2	11	2242	AAH02427.2
	BM998653.1
	BX537669.1	1	3969

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv831169	Chr.7:143188183 - 143348025 on Build GRCh38	Loss	TMEM139 LOC105375545 TAS2R40 CASP2 CLCN1 GSTK1
nsv5984	Chr.7:143305004 - 143350170 on Build GRCh38	Deletion	CASP2 CLCN1

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

luteolysis
neural retina development
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
brain development
aging
intrinsic apoptotic signaling pathway in response to DNA damage
protein processing
ectopic germ cell programmed cell death
regulation of apoptotic process
positive regulation of apoptotic process
positive regulation of neuron apoptotic process
cellular response to mechanical stimulus
apoptotic signaling pathway
extrinsic apoptotic signaling pathway in absence of ligand
execution phase of apoptosis
positive regulation of apoptotic signaling pathway

Function(s)

cysteine-type endopeptidase activity
protein binding
enzyme binding
protein domain specific binding
cysteine-type endopeptidase activity involved in apoptotic process