Hs01496923_cn

• Gene Symbol: GRM2
• Assay Reference Genome Location: Chr.3:51717829 on build GRCh38
• Cytoband: 3p21.2

Target Gene Details

• Entrez Gene ID: 2912
• Gene Name: glutamate metabotropic receptor 2
• Gene Aliases: GLUR2, GPRC1B, MGLUR2, mGlu2
• Location: Chr.3:51707033-51718616 on Build GRCh38
• Assay Gene Location: Overlaps Exon 6 - Intron 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GRM2	NM_000839.3			NP_000830.2
	NM_001130063.1			NP_001123535.1
	XM_011533635.1			XP_011531937.1
	XM_011533636.1			XP_011531938.1
	XM_011533637.1			XP_011531939.1
	XM_011533638.2			XP_011531940.1
	XM_011533639.2			XP_011531941.1
	XM_011533640.2			XP_011531942.1
	XM_011533641.2			XP_011531943.1
	XM_011533643.1			XP_011531945.1
	XM_011533644.1			XP_011531946.1
	XM_011533645.1			XP_011531947.1
	XM_011533646.2			XP_011531948.1
	XM_011533647.1			XP_011531949.1
	XM_017006271.1			XP_016861760.1
	AB209164.1			BAD92401.1
	AK289984.1
	AK313056.1
	AK315816.1
	AY999299.1			AAY14640.1
	BC041447.1			AAH41447.1
	BC113615.1
	BC113619.1
	BX648951.1
	EU432122.1
	L35318.1			AAA76855.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv508921	Chr.3:51647199 - 51803073 on Build GRCh38	Insertion	TEX264 GRM2 IQCF6 RAD54L2
nsv954856	Chr.3:51687685 - 51721184 on Build GRCh38	Deletion	TEX264 GRM2

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

G-protein coupled receptor

Gene Ontology Categories:

Process(es)

negative regulation of adenylate cyclase activity
adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway
chemical synaptic transmission
glutamate secretion
regulation of synaptic transmission, glutamatergic

Function(s)

group II metabotropic glutamate receptor activity
G-protein coupled receptor activity
calcium channel regulator activity
protein binding
glutamate receptor activity