Hs01515198_cn

• Gene Symbol: ITPKB
• Assay Reference Genome Location: Chr.1:226633772 on build GRCh38
• Cytoband: 1q42.12

Target Gene Details

• Entrez Gene ID: 3707
• Gene Name: inositol-trisphosphate 3-kinase B
• Gene Aliases: IP3-3KB, IP3K, IP3K-B, IP3KB, PIG37
• Location: Chr.1:226631690-226739327 on Build GRCh38
• Assay Gene Location: Within Exon 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ITPKB	NM_002221.3	8	4080	NP_002212.3
	AJ242780.1	7	3797	CAC40650.1
	X57206.1	7	2419	CAA40491.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv470779	Chr.1:226590731 - 226645603 on Build GRCh38	Loss	STUM ITPKB
nsv522446	Chr.1:226597829 - 226736237 on Build GRCh38	Loss	STUM ITPKB-IT1 ITPKB
nsv4755	Chr.1:226608634 - 226643907 on Build GRCh38	Insertion	STUM ITPKB

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

kinase

Gene Ontology Categories:

Process(es)

MAPK cascade
regulation of protein phosphorylation
myeloid cell homeostasis
signal transduction
cell surface receptor signaling pathway
inositol trisphosphate metabolic process
negative regulation of neutrophil apoptotic process
common myeloid progenitor cell proliferation
inositol phosphate metabolic process
positive thymic T cell selection
negative regulation of myeloid cell differentiation
positive regulation of Ras protein signal transduction
positive regulation of alpha-beta T cell differentiation
cellular response to calcium ion

Function(s)

protein binding
calmodulin binding
ATP binding
inositol-1,4,5-trisphosphate 3-kinase activity