Hs01517963_cn

• Gene Symbol: TRIM28
• Assay Reference Genome Location: Chr.19:58548497 on build GRCh38
• Cytoband: 19q13.43

Target Gene Details

• Entrez Gene ID: 10155
• Gene Name: tripartite motif containing 28
• Gene Aliases: KAP1, PPP1R157, RNF96, TF1B, TIF1B
• Location: Chr.19:58544469-58550715 on Build GRCh38
• Assay Gene Location: Overlaps Intron 8 - Exon 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TRIM28	NM_005762.2			NP_005753.1
	AK131063.1
	AK225760.1
	AK313478.1
	BC004978.1			AAH04978.1
	BC052986.2			AAH52986.1
	U78773.1			AAB37341.1
	U95040.1			AAB51517.1
	X97548.1			CAA66150.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1057206	Chr.19:58546716 - 58586475 on Build GRCh38	Gain	TRIM28 UBE2M MZF1 CENPBD1P1 MIR6807 CHMP2A MZF1-AS1
dgv3687n100	Chr.19:58473466 - 58586475 on Build GRCh38	Gain	TRIM28 UBE2M MZF1 ZNF446 ZBTB45 CENPBD1P1 ZNF324 SLC27A5 MIR6807 CHMP2A MZF1-AS1
nsv515731	Chr.19:58320453 - 58576112 on Build GRCh38	Gain+Loss	ZNF446 ZNF324B ZNF837 CENPBD1P1 SLC27A5 ZNF132 MIR4754 ZNF584 LOC105372483 ZNF497 MZF1 A1BG-AS1 A1BG TRIM28 UBE2M MIR6806 ZSCAN22 ZBTB45 LOC100419840 ZNF324 RPS5 RNF225 MIR6807 CHMP2A LOC100506634 MZF1-AS1
nsv952156	Chr.19:58466134 - 58600733 on Build GRCh38	Deletion	TRIM28 UBE2M MZF1 ZNF446 ZBTB45 CENPBD1P1 ZNF324 SLC27A5 MIR6807 CHMP2A MZF1-AS1
nsv1160670	Chr.19:58433008 - 58586487 on Build GRCh38	Deletion	MZF1 ZNF446 ZNF324B CENPBD1P1 SLC27A5 ZNF132 TRIM28 UBE2M ZBTB45 ZNF324 MIR6807 CHMP2A MZF1-AS1
nsv828657	Chr.19:58483484 - 58585740 on Build GRCh38	Gain	TRIM28 UBE2M MZF1 ZNF446 ZBTB45 CENPBD1P1 SLC27A5 MIR6807 CHMP2A MZF1-AS1
dgv3688n100	Chr.19:58506055 - 58586475 on Build GRCh38	Gain	TRIM28 UBE2M MZF1 ZBTB45 CENPBD1P1 SLC27A5 MIR6807 CHMP2A MZF1-AS1
nsv1057077	Chr.19:58411953 - 58586475 on Build GRCh38	Gain	MZF1 ZNF446 ZNF324B CENPBD1P1 SLC27A5 ZNF132 TRIM28 UBE2M ZBTB45 ZNF324 MIR6807 CHMP2A MZF1-AS1 ZNF584

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
epithelial to mesenchymal transition
DNA repair
transcription initiation from RNA polymerase II promoter
Ras protein signal transduction
embryo implantation
protein ubiquitination
covalent chromatin modification
protein sumoylation
positive regulation of transcription factor import into nucleus
DNA methylation involved in embryo development
innate immune response
positive regulation of DNA repair
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
protein autophosphorylation
protein oligomerization
convergent extension involved in axis elongation
embryonic placenta morphogenesis
positive regulation of methylation-dependent chromatin silencing
negative regulation of DNA demethylation
negative regulation of viral release from host cell
regulation of genetic imprinting

Function(s)

RNA polymerase II transcription coactivator activity
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
protein kinase activity
ubiquitin-protein transferase activity
protein binding
zinc ion binding
ligase activity
ubiquitin protein ligase binding
Krueppel-associated box domain binding
sequence-specific DNA binding
poly(A) RNA binding
chromo shadow domain binding
promoter-specific chromatin binding