Hs01532649_cn

• Gene Symbol: CARD18
• Assay Reference Genome Location: Chr.11:105139027 on build GRCh38
• Cytoband: 11q22.3

Target Gene Details

• Entrez Gene ID: 59082
• Gene Name: caspase recruitment domain family member 18
• Gene Aliases: ICEBERG, UNQ5804, pseudo-ICE
• Location: Chr.11:105137721-105139734 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CARD18	NM_021571.3			NP_067546.1
	AF208005.1			AAG23528.1
	AI189838.1	2	373
	AY358231.1			AAQ88598.1
	BC131610.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1052674	Chr.11:104111970 - 107043401 on Build GRCh38	Loss	MSANTD4 AASDHPPT MIR7641-1 CASP1 LOC643733 CARD16 CARD18 LOC102723895 CASP4 GUCY1A2 CASP12 KBTBD3 CASP1P2 LOC105369473 CARD17 GRIA4 LOC101928535 PDGFD CASP5
esv2750978	Chr.11:104094062 - 105475331 on Build GRCh38	Gain	MIR7641-1 CASP1 LOC643733 CARD17 CARD16 CARD18 LOC102723895 CASP4 PDGFD CASP12 CASP5 CASP1P2
nsv468862	Chr.11:104903287 - 105372644 on Build GRCh38	Gain	CASP1 LOC643733 CARD17 CARD16 CARD18 CASP4 CASP5 CASP1P2
nsv1038877	Chr.11:104166130 - 105422422 on Build GRCh38	Gain	MIR7641-1 CASP1 LOC643733 CARD17 CARD16 CARD18 LOC102723895 CASP4 CASP12 CASP5 CASP1P2

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

inflammatory response
negative regulation of endopeptidase activity
regulation of apoptotic process

Function(s)

cysteine-type endopeptidase inhibitor activity