Hs01568743_cn

• Gene Symbol: BIRC5
• Assay Reference Genome Location: Chr.17:78224706 on build GRCh38
• Cytoband: 17q25.3

Target Gene Details

• Entrez Gene ID: 332
• Gene Name: baculoviral IAP repeat containing 5
• Gene Aliases: API4, EPR-1
• Location: Chr.17:78214196-78225635 on Build GRCh38
• Assay Gene Location: Within Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
BIRC5	NM_001012270.1	3	1584	NP_001012270.1
	NM_001012271.1	5	1771	NP_001012271.1
	NM_001168.2	4	1702	NP_001159.2
	AF077350.1			AAD34226.1
	AK223428.1			BAD97148.1
	AL519719.3	1	277
	BC008718.2			AAH08718.1
	BC034148.1			AAH34148.1
	BC065497.1			AAH65497.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv524306	Chr.17:78183449 - 78280693 on Build GRCh38	Gain	LOC105371910 TMEM235 LOC100996291 TK1 AFMID BIRC5
nsv952373	Chr.17:78214820 - 78283319 on Build GRCh38	Deletion	LOC105371910 TMEM235 LOC100996291 BIRC5

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

transcription, DNA-templated
protein phosphorylation
apoptotic process
sister chromatid cohesion
positive regulation of cell proliferation
regulation of signal transduction
protein ubiquitination
protein sumoylation
protein complex localization
regulation of apoptotic process
negative regulation of apoptotic process
negative regulation of transcription, DNA-templated
cell division
mitotic spindle assembly
inhibition of cysteine-type endopeptidase activity involved in apoptotic process

Function(s)

ubiquitin-protein transferase activity
cysteine-type endopeptidase inhibitor activity
protein binding
microtubule binding
Ran GTPase binding
enzyme binding
identical protein binding
metal ion binding
chaperone binding