Hs01625513_cn

• Gene Symbol: FADD
• Assay Reference Genome Location: Chr.11:70206603 on build GRCh38
• Cytoband: 11q13.3

Target Gene Details

• Entrez Gene ID: 8772
• Gene Name: Fas associated via death domain
• Gene Aliases: GIG3, MORT1
• Location: Chr.11:70203163-70207402 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
FADD	NM_003824.3	2	1054	NP_003815.1
	AL575732.1
	BC000334.2	2	902	AAH00334.1
	U24231.1	2	886	AAA86517.1
	X84709.1	2	901	CAA59197.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv555376	Chr.11:70156780 - 70248052 on Build GRCh38	Loss	FADD ANO1

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

positive regulation of T cell mediated cytotoxicity
positive regulation of adaptive immune response
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
cell surface receptor signaling pathway
extrinsic apoptotic signaling pathway via death domain receptors
positive regulation of interferon-gamma production
positive regulation of interleukin-8 production
positive regulation of tumor necrosis factor production
T cell differentiation in thymus
TRIF-dependent toll-like receptor signaling pathway
TRAIL-activated apoptotic signaling pathway
positive regulation of activated T cell proliferation
T cell homeostasis
positive regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
innate immune response
positive regulation of macrophage differentiation
positive regulation of proteolysis
positive regulation of transcription from RNA polymerase II promoter
lymph node development
spleen development
thymus development
protein heterooligomerization
defense response to virus
positive regulation of type I interferon-mediated signaling pathway
negative regulation of necroptotic process
negative regulation of activation-induced cell death of T cells
cellular response to mechanical stimulus
death-inducing signaling complex assembly
motor neuron apoptotic process
apoptotic signaling pathway
extrinsic apoptotic signaling pathway
extrinsic apoptotic signaling pathway in absence of ligand
activation of cysteine-type endopeptidase activity
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
necroptotic signaling pathway
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation
positive regulation of extrinsic apoptotic signaling pathway

Function(s)

protease binding
death receptor binding
tumor necrosis factor receptor binding
protein binding
protein complex binding
tumor necrosis factor receptor superfamily binding
death effector domain binding
identical protein binding
caspase binding