Hs01627715_cn

• Gene Symbol: TRADD
• Assay Reference Genome Location: Chr.16:67156244 on build GRCh38
• Cytoband: 16q22.1

Target Gene Details

• Entrez Gene ID: 8717
• Gene Name: TNFRSF1A associated via death domain
• Gene Aliases: Hs.89862
• Location: Chr.16:67154185-67159909 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TRADD	NM_001323552.1			NP_001310481.1
	NM_003789.3			NP_003780.1
	XM_005256213.3			XP_005256270.1
	XM_017023815.1			XP_016879304.1
	AK090673.1
	AK301593.1
	AK315654.1
	BC004491.2			AAH04491.1
	BG717460.1
	BT006934.1			AAP35580.1
	DA353575.1
	L41690.1			AAA98482.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv522852	Chr.16:67153308 - 68071571 on Build GRCh38	Gain	KCTD19 EXOC3L1 CENPT PSKH1 ZDHHC1 PLEKHG4 LOC100131303 MIR328 SLC9A5 DPEP3 LRRC36 DUS2 SLC12A4 AGRP NOL3 DPEP2 CTCF TPPP3 TMEM208 LOC100505942 ELMO3 ACD TRADD FHOD1 LRRC29 ATP6V0D1 LCAT NRN1L RANBP10 EDC4 HSF4 PARD6A ENKD1 FBXL8 LOC107984813 NUTF2 GFOD2 THAP11 KIAA0895L TSNAXIP1 C16orf86 E2F4 LOC105369155 HSD11B2 FAM65A DDX28 PSMB10 CARMIL2 CTRL
nsv827707	Chr.16:67148355 - 67289296 on Build GRCh38	Loss	MIR328 ELMO3 TRADD SLC9A5 FHOD1 LRRC29 NOL3 B3GNT9 KIAA0895L EXOC3L1 C16orf70 HSF4 E2F4 LOC105369155 FBXL8 TMEM208 PLEKHG4
nsv952044	Chr.16:67141198 - 67244397 on Build GRCh38	Deletion	MIR328 ELMO3 TRADD FHOD1 LRRC29 NOL3 B3GNT9 KIAA0895L EXOC3L1 C16orf70 HSF4 E2F4 LOC105369155 FBXL8 TMEM208
nsv524363	Chr.16:67136529 - 68071571 on Build GRCh38	Loss	KCTD19 B3GNT9 EXOC3L1 C16orf70 CENPT PSKH1 ZDHHC1 PLEKHG4 LOC100131303 MIR328 SLC9A5 DPEP3 LRRC36 DUS2 SLC12A4 AGRP NOL3 DPEP2 CTCF TPPP3 TMEM208 LOC100505942 ELMO3 ACD TRADD FHOD1 LRRC29 ATP6V0D1 LCAT NRN1L RANBP10 EDC4 HSF4 PARD6A ENKD1 FBXL8 LOC107984813 NUTF2 GFOD2 THAP11 KIAA0895L TSNAXIP1 C16orf86 E2F4 LOC105369155 HSD11B2 FAM65A DDX28 PSMB10 CARMIL2 CTRL

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
signal transduction
I-kappaB kinase/NF-kappaB signaling
extrinsic apoptotic signaling pathway via death domain receptors
regulation of tumor necrosis factor-mediated signaling pathway
regulation of necrotic cell death
tumor necrosis factor-mediated signaling pathway
positive regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of NF-kappaB transcription factor activity
protein heterooligomerization
positive regulation of hair follicle development
death-inducing signaling complex assembly
extrinsic apoptotic signaling pathway
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

Function(s)

signal transducer activity
tumor necrosis factor receptor binding
protein binding
kinase binding
protein complex binding
identical protein binding
binding, bridging
death domain binding