Hs01644185_cn

• Gene Symbol: CTLA4
• Assay Reference Genome Location: Chr.2:203873004 on build GRCh38
• Cytoband: 2q33.2

Target Gene Details

• Entrez Gene ID: 1493
• Gene Name: cytotoxic T-lymphocyte associated protein 4
• Gene Aliases: ALPS5, CD, CD152, CELIAC3, CTLA-4, GRD4, GSE, IDDM12
• Location: Chr.2:203867788-203873960 on Build GRCh38
• Assay Gene Location: Within Exon 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CTLA4	NM_001037631.2	3	909	NP_001032720.1
	NM_005214.4	4	1019	NP_005205.2
	AF414120.1	4	1019	AAL07473.1
	BC069566.1			AAH69566.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1001799	Chr.2:202908732 - 205615330 on Build GRCh38	Gain	PARD3B RAPH1 ICOS ABI2 CYP20A1 NBEAL1 RPL12P16 CD28 CTLA4 CARF WDR12

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

immunoglobulin receptor superfamily

Gene Ontology Categories:

Process(es)

adaptive immune response
immune response
cellular response to DNA damage stimulus
negative regulation of B cell proliferation
T cell costimulation
positive regulation of apoptotic process
negative regulation of regulatory T cell differentiation
B cell receptor signaling pathway

Function(s)

protein binding