Hs01685742_cn

• Gene Symbol: SLC17A7
• Assay Reference Genome Location: Chr.19:49430644 on build GRCh38
• Cytoband: 19q13.33

Target Gene Details

• Entrez Gene ID: 57030
• Gene Name: solute carrier family 17 member 7
• Gene Aliases: BNPI, VGLUT1
• Location: Chr.19:49429398-49441551 on Build GRCh38
• Assay Gene Location: Within Exon 12

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SLC17A7	NM_020309.3	12	1730	NP_064705.1
	AB032436.1	12	1579	BAA92875.1
	AK091061.1	7	953
	AK289622.1	9	1138
	AK294226.1	12	1536
	AK294405.1	12	1579
	BC059379.1	12	1705	AAH59379.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv9739	Chr.19:47901840 - 50143063 on Build GRCh38	Gain+Loss	SNAR-A8 IL4I1 PRMT1 NUCB1 SNAR-G1 SNORD35B MIR150 FAM83E SPACA4 DKKL1 RPL13A ATF5 CGB3 C19orf68 PPP1R15A SNAR-A6 VRK3 PLA2G4C PTOV1-AS1 SNAR-A14 GRIN2D SNAR-C1 SNORD35A PIH1D1 C19orf73 NTF4 MIR6800 SNAR-A5 PLEKHA4 CARD8-AS1 SNAR-B1 SNAR-A7 MIR6798 TULP2 SIGLEC16 ELSPBP1 SNORD33 FTL NUCB1-AS1 GRWD1 MIR4324 SNRNP70 MIR6799 RUVBL2 CA11 AP2A1 PRR12 SNAR-B2 SULT2B1 ALDH16A1 BCL2L12 SLC6A16 FLT3LG LHB HSD17B14 MIR5088 ZNF114 RRAS CD37 CCDC155 PPFIA3 SNAR-C3 LIN7B NOSIP GYS1 SNAR-A10 TBC1D17 RCN3 SNAR-D TSKS CGB8 AKT1S1 HRC CGB2 FLJ26850 SNAR-A3 MIR4749 RPS11 BAX GFY RPL18 ADM5 FGF21 SNAR-A13 SNAR-A1 CGB1 SPHK2 PNKP CGB7 TMEM143 PTOV1-AS2 DBP LMTK3 KDELR1 SNAR-A12 MED25 IZUMO1 SNAR-A11 SNAR-C4 SNAR-G2 CARD8 SIGLEC11 SNAR-A4 PLA2G4C-AS1 DHDH SCAF1 SEC1P LIG1 BCAT2 IRF3 BSPH1 LOC105372430 SNAR-C5 LOC100287477 KCNA7 TRPM4 NUP62 CYTH2 FUT2 CCDC114 LOC105447645 CABP5 EMP3 LOC101059948 KCNJ14 PTH2 FUT1 LOC101928295 MIR4750 SNORD32A ZNF473 CPT1C SNORD34 FCGRT TEAD2 FUZ SNAR-A2 CGB5 SNAR-C2 SNAR-A9 MAMSTR NTN5 MIR4751 SLC17A7 RASIP1 SYNGR4 PTOV1 PRRG2
dgv52n68	Chr.19:49286685 - 49456131 on Build GRCh38	Loss	ALDH16A1 MIR4324 DKKL1 PIH1D1 SLC17A7 SLC6A16 CD37 TEAD2 CCDC155 GFY PTH2 LOC101928295
nsv953599	Chr.19:49386444 - 49506743 on Build GRCh38	Deletion	SNORD32A ALDH16A1 SNORD35A SNORD33 PIH1D1 SNORD34 FLT3LG SNORD35B MIR150 SLC17A7 RPL13A CCDC155 RPS11 GFY PTH2 LOC101928295

More Information

Additional Information:

For this assay, SNP(s) [rs112656149] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

secondary carrier transporter

Gene Ontology Categories:

Process(es)

neural retina development
ion transport
phosphate ion transport
neurotransmitter transport
brain development
long-term memory
glutamate secretion
synaptic transmission, glutamatergic
phosphate ion transmembrane transport
sodium ion transmembrane transport
sequestering of neurotransmitter
sodium-dependent phosphate transport
L-glutamate import
excitatory postsynaptic potential
L-glutamate transmembrane transport
synaptic vesicle lumen acidification
chloride transmembrane transport

Function(s)

L-glutamate transmembrane transporter activity
inorganic phosphate transmembrane transporter activity
extracellular-glutamate-gated chloride channel activity
sodium:inorganic phosphate symporter activity
sodium-dependent phosphate transmembrane transporter activity