Hs01718059_cn

• Gene Symbol: NUDT18
• Assay Reference Genome Location: Chr.8:22109898 on build GRCh38
• Cytoband: 8p21.3

Target Gene Details

• Entrez Gene ID: 79873
• Gene Name: nudix hydrolase 18
• Gene Aliases: MTH3
• Location: Chr.8:22106872-22110355 on Build GRCh38
• Assay Gene Location: Overlaps Intron 1 - Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NUDT18	XM_011544650.1			XP_011542952.1
	AK124446.1			BAC85853.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv465613	Chr.8:22046701 - 22197835 on Build GRCh38	Loss	NUDT18 LGI3 FGF17 FAM160B2 SFTPC REEP4 HR BMP1 DMTN
nsv528590	Chr.8:22034428 - 22168131 on Build GRCh38	Loss	NUDT18 NPM2 LGI3 FGF17 FAM160B2 SFTPC REEP4 HR BMP1 DMTN
nsv610765	Chr.8:22043573 - 22149780 on Build GRCh38	Loss	NUDT18 LGI3 FGF17 FAM160B2 REEP4 HR DMTN
nsv951112	Chr.8:22023690 - 22135287 on Build GRCh38	Deletion	NUDT18 NPM2 FGF17 FAM160B2 HR DMTN
nsv527293	Chr.8:22106867 - 22163524 on Build GRCh38	Loss	NUDT18 LGI3 SFTPC REEP4 HR
nsv831263	Chr.8:22031088 - 22184413 on Build GRCh38	Loss	NUDT18 NPM2 LGI3 FGF17 FAM160B2 SFTPC REEP4 HR BMP1 DMTN
nsv470204	Chr.8:22094715 - 22171155 on Build GRCh38	Loss	NUDT18 LGI3 FAM160B2 SFTPC REEP4 HR BMP1
dgv12054n54	Chr.8:22045805 - 22251098 on Build GRCh38	Loss	NUDT18 POLR3D PHYHIP LGI3 MIR320A FGF17 FAM160B2 SFTPC REEP4 HR BMP1 DMTN
nsv831264	Chr.8:22093700 - 22328040 on Build GRCh38	Gain+Loss	NUDT18 POLR3D PHYHIP LGI3 PIWIL2 MIR320A FAM160B2 SFTPC REEP4 HR BMP1 LOC100507071
esv2759604	Chr.8:20675533 - 23254096 on Build GRCh38	Loss	POLR3D XPO7 TNFRSF10D PIWIL2 EGR3 GFRA2 FAM160B2 SFTPC LOC254896 NPM2 CCAR2 LGI3 MIR320A SLC39A14 TNFRSF10B CHMP7 LOC101929237 REEP4 HR LOC100507071 LOC101929172 DMTN PEBP4 C8orf58 PDLIM2 LOC102467222 PHYHIP TNFRSF10A LOC389641 LOC286114 BIN3-IT1 LOC286059 RHOBTB2 PPP3CC DOK2 BMP1 NUDT18 BIN3 LOC107984124 FGF17 LOC107986876 SORBS3 TNFRSF10C

More Information

Additional Information:

For this assay, SNP(s) [rs77693145] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

hydrolase

Gene Ontology Categories:

Process(es)

nucleobase-containing small molecule catabolic process
dADP catabolic process
dGDP catabolic process
GDP catabolic process

Function(s)

magnesium ion binding
protein binding
8-oxo-dGDP phosphatase activity
8-oxo-GDP phosphatase activity
8-hydroxy-dADP phosphatase activity