Hs01747318_cn

• Gene Symbol: MST1
• Assay Reference Genome Location: Chr.3:49683957 on build GRCh38
• Cytoband: 3p21.31

Target Gene Details

• Entrez Gene ID: 4485
• Gene Name: macrophage stimulating 1
• Gene Aliases: D3F15S2, DNF15S2, HGFL, MSP, NF15S2
• Location: Chr.3:49683947-49689528 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 18

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MST1	NM_020998.3			NP_066278.3
	XM_006713166.1			XP_006713229.1
	XM_011533732.1			XP_011532034.1
	XM_017006460.1			XP_016861949.1
	XM_017006461.1			XP_016861950.1
	XM_017006462.1			XP_016861951.1
	XM_017006463.1			XP_016861952.1
	XM_017006464.1			XP_016861953.1
	AK222893.1			BAD96613.1
	BC048330.1			AAH48330.1
	BM672747.1
	L11924.1			AAA59872.1
	M74178.1			AAA50165.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv471425	Chr.3:49683948 - 49688763 on Build GRCh38	Gain	RNF123 MST1
nsv1148681	Chr.3:49683166 - 49692167 on Build GRCh38	Duplication	APEH RNF123 MST1
esv28815	Chr.3:49683318 - 49698418 on Build GRCh38	Gain+Loss	APEH RNF123 MST1
nsv1141429	Chr.3:49676267 - 49693067 on Build GRCh38	Duplication	APEH RNF123 MST1
nsv822077	Chr.3:49683967 - 49697093 on Build GRCh38	Gain	RNF123 MST1
nsv508217	Chr.3:49578013 - 49732463 on Build GRCh38	Deletion	APEH IP6K1 BSN RNF123 AMIGO3 GMPPB MST1
nsv820990	Chr.3:49683218 - 49698478 on Build GRCh38	Duplication	APEH RNF123 MST1

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

serine protease

Gene Ontology Categories:

Process(es)

proteolysis
biological_process
negative regulation of gluconeogenesis
hepatocyte growth factor receptor signaling pathway
regulation of cAMP-dependent protein kinase activity

Function(s)

molecular_function
serine-type endopeptidase activity
protein binding
receptor tyrosine kinase binding