Hs01762828_cn

• Gene Symbol: ADRB3
• Assay Reference Genome Location: Chr.8:37963673 on build GRCh38
• Cytoband: 8p11.23

Target Gene Details

• Entrez Gene ID: 155
• Gene Name: adrenoceptor beta 3
• Gene Aliases: BETA3AR
• Location: Chr.8:37962995-37966666 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ADRB3	NM_000025.2	2	1969	NP_000016.1
	X70811.1	2	1897	CAA50141.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv610947	Chr.8:37935047 - 38054626 on Build GRCh38	Loss	EIF4EBP1 ADRB3 GOT1L1

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

G-protein coupled receptor

Gene Ontology Categories:

Process(es)

temperature homeostasis
diet induced thermogenesis
vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure
desensitization of G-protein coupled receptor protein signaling pathway by arrestin
carbohydrate metabolic process
generation of precursor metabolites and energy
energy reserve metabolic process
receptor-mediated endocytosis
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
activation of adenylate cyclase activity
cell-cell signaling
aging
response to cold
heat generation
negative regulation of multicellular organism growth
eating behavior
positive regulation of MAPK cascade
response to antibiotic
brown fat cell differentiation
adenylate cyclase-activating adrenergic receptor signaling pathway

Function(s)

beta-adrenergic receptor activity
protein binding
beta3-adrenergic receptor activity
beta-3 adrenergic receptor binding
protein homodimerization activity
epinephrine binding
norepinephrine binding