Hs01806210_cn

• Gene Symbol: TRADD
• Assay Reference Genome Location: Chr.16:67154803 on build GRCh38
• Cytoband: 16q22.1

Target Gene Details

• Entrez Gene ID: 8717
• Gene Name: TNFRSF1A associated via death domain
• Gene Aliases: Hs.89862
• Location: Chr.16:67154185-67159909 on Build GRCh38
• Assay Gene Location: Within Exon 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TRADD	NM_001323552.1	5	878	NP_001310481.1
	NM_003789.3	5	865	NP_003780.1
	XM_005256213.3	5	1382	XP_005256270.1
	XM_017023815.1	5	931	XP_016879304.1
	AK090673.1	3	1229
	AK315654.1	5	1258
	BC004491.2	5	842	AAH04491.1
	BT006934.1	4	785	AAP35580.1
	CA426418.1	1	632
	L41690.1	5	833	AAA98482.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv522852	Chr.16:67153308 - 68071571 on Build GRCh38	Gain	LRRC36 PLEKHG4 ACD DUS2 ATP6V0D1 SLC12A4 LOC100131303 PARD6A SLC9A5 ENKD1 DPEP3 LOC105369155 DPEP2 PSKH1 TSNAXIP1 MIR328 FBXL8 RANBP10 LRRC29 KIAA0895L LOC107984813 PSMB10 DDX28 ZDHHC1 NUTF2 THAP11 CTRL FHOD1 TRADD LOC100505942 GFOD2 EDC4 NRN1L E2F4 CTCF C16orf86 KCTD19 TPPP3 LCAT HSD11B2 CENPT AGRP HSF4 EXOC3L1 TMEM208 FAM65A ELMO3 CARMIL2 NOL3
nsv827707	Chr.16:67148355 - 67289296 on Build GRCh38	Loss	PLEKHG4 LOC105369155 B3GNT9 FHOD1 TRADD MIR328 HSF4 EXOC3L1 TMEM208 FBXL8 E2F4 LRRC29 KIAA0895L ELMO3 SLC9A5 NOL3 C16orf70
nsv952044	Chr.16:67141198 - 67244397 on Build GRCh38	Deletion	LOC105369155 B3GNT9 FHOD1 TRADD MIR328 HSF4 EXOC3L1 TMEM208 FBXL8 E2F4 LRRC29 KIAA0895L ELMO3 NOL3 C16orf70
nsv524363	Chr.16:67136529 - 68071571 on Build GRCh38	Loss	LRRC36 PLEKHG4 ACD DUS2 ATP6V0D1 SLC12A4 LOC100131303 PARD6A SLC9A5 ENKD1 DPEP3 LOC105369155 DPEP2 PSKH1 TSNAXIP1 MIR328 FBXL8 RANBP10 LRRC29 KIAA0895L LOC107984813 PSMB10 DDX28 ZDHHC1 NUTF2 THAP11 CTRL FHOD1 TRADD LOC100505942 GFOD2 EDC4 NRN1L E2F4 CTCF C16orf86 C16orf70 KCTD19 TPPP3 B3GNT9 LCAT HSD11B2 CENPT AGRP HSF4 EXOC3L1 TMEM208 FAM65A ELMO3 CARMIL2 NOL3

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
signal transduction
I-kappaB kinase/NF-kappaB signaling
extrinsic apoptotic signaling pathway via death domain receptors
regulation of tumor necrosis factor-mediated signaling pathway
regulation of necrotic cell death
tumor necrosis factor-mediated signaling pathway
positive regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of NF-kappaB transcription factor activity
protein heterooligomerization
positive regulation of hair follicle development
death-inducing signaling complex assembly
extrinsic apoptotic signaling pathway
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

Function(s)

signal transducer activity
tumor necrosis factor receptor binding
protein binding
kinase binding
protein complex binding
identical protein binding
binding, bridging
death domain binding