Hs01855822_cn

• Gene Symbol: TNIP2
• Assay Reference Genome Location: Chr.4:2745530 on build GRCh38
• Cytoband: 4p16.3

Target Gene Details

• Entrez Gene ID: 79155
• Gene Name: TNFAIP3 interacting protein 2
• Gene Aliases: ABIN2, FLIP1, KLIP
• Location: Chr.4:2741660-2756376 on Build GRCh38
• Assay Gene Location: Overlaps Intron 2 - Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TNIP2	NM_001161527.1			NP_001154999.1
	NM_001292016.1			NP_001278945.1
	NM_024309.3			NP_077285.3
	AF372839.1			AAM21315.1
	AJ304866.1			CAC34835.1
	AK026176.1			BAB15382.1
	AK096296.1
	BC002740.2			AAH02740.2
	BX386180.2
	DA421921.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv470002	Chr.4:2699371 - 2834901 on Build GRCh38	Loss	TNIP2 SH3BP2 FAM193A
esv2726835	Chr.4:2019561 - 2959568 on Build GRCh38	Deletion	NOP14 TNIP2 RNF4 MFSD10 NAT8L SH3BP2 MXD4 FAM193A HAUS3 POLN CFAP99 NOP14-AS1 ADD1 MIR4800 ZFYVE28 C4orf48
nsv516797	Chr.4:2721804 - 2834901 on Build GRCh38	Loss	TNIP2 SH3BP2 FAM193A

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

transcription, DNA-templated
apoptotic process
inflammatory response
I-kappaB kinase/NF-kappaB signaling
CD40 signaling pathway
toll-like receptor 2 signaling pathway
toll-like receptor 3 signaling pathway
toll-like receptor 9 signaling pathway
positive regulation of macrophage activation
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of transcription from RNA polymerase II promoter
protein stabilization
positive regulation of B cell activation
stress-activated MAPK cascade
interleukin-1-mediated signaling pathway
cellular response to lipopolysaccharide
negative regulation of endothelial cell apoptotic process

Function(s)

protein binding
protein kinase binding
polyubiquitin binding