Hs01861316_cn

• Gene Symbol: REXO1
• Assay Reference Genome Location: Chr.19:1815821 on build GRCh38
• Cytoband: 19p13.3

Target Gene Details

• Entrez Gene ID: 57455
• Gene Name: RNA exonuclease 1 homolog
• Gene Aliases: ELOABP1, EloA-BP1, REX1, TCEB3BP1
• Location: Chr.19:1815246-1848684 on Build GRCh38
• Assay Gene Location: Within Exon 17

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
REXO1	NM_020695.3	16	4006	NP_065746.3
	XM_011528144.1	15	4138	XP_011526446.1
	XM_011528146.2	15	4402	XP_011526448.1
	XM_017027028.1	15	4111	XP_016882517.1
	XM_017027029.1	16	4068	XP_016882518.1
	AB032964.1	16	3994
	AK301030.1	11	1759
	BC032244.1	16	4016	AAH32244.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv567n67	Chr.19:1814820 - 1816718 on Build GRCh38	Gain	MIR1909 REXO1
esv3893156	Chr.19:1766738 - 2115791 on Build GRCh38	Loss	MOB3A KLF16 BTBD2 ATP8B3 AP3D1 IZUMO4 CSNK1G2 CSNK1G2-AS1 SCAMP4 ABHD17A MKNK2 ADAT3 ONECUT3 MIR1909 REXO1 LOC100288123
esv32942	Chr.19:1320268 - 1999205 on Build GRCh38	Gain+Loss	MUM1 KLF16 BTBD2 ATP8B3 APC2 MBD3 GAMT CSNK1G2-AS1 ADAMTSL5 UQCR11 ADAT3 ONECUT3 LOC100288123 NDUFS7 RPS15 REEP6 TCF3 CSNK1G2 PLK5 SCAMP4 ABHD17A MEX3D PCSK4 DAZAP1 MIR1909 C19orf25 REXO1
nsv470107	Chr.19:1782799 - 2100347 on Build GRCh38	Loss	MOB3A KLF16 BTBD2 ATP8B3 IZUMO4 CSNK1G2 CSNK1G2-AS1 SCAMP4 ABHD17A MKNK2 ADAT3 MIR1909 REXO1 LOC100288123
nsv1160560	Chr.19:1791100 - 1916393 on Build GRCh38	Deletion	SCAMP4 KLF16 ABHD17A ATP8B3 ADAT3 MIR1909 REXO1 LOC100288123
nsv578337	Chr.19:1808864 - 1904613 on Build GRCh38	Gain	KLF16 ABHD17A ATP8B3 MIR1909 REXO1 LOC100288123
nsv828384	Chr.19:1815595 - 1816286 on Build GRCh38	Gain	MIR1909 REXO1
nsv953942	Chr.19:1371602 - 2057401 on Build GRCh38	Deletion	MUM1 KLF16 BTBD2 ATP8B3 APC2 MBD3 GAMT CSNK1G2-AS1 ADAMTSL5 UQCR11 MKNK2 ADAT3 ONECUT3 LOC100288123 NDUFS7 RPS15 REEP6 TCF3 CSNK1G2 PLK5 SCAMP4 ABHD17A MEX3D PCSK4 DAZAP1 MIR1909 C19orf25 REXO1

More Information

Additional Information:

For this assay, SNP(s) [rs569769927] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

exoribonuclease

Gene Ontology Categories:

Process(es)

nucleic acid phosphodiester bond hydrolysis

Function(s)

nucleic acid binding
exonuclease activity