Hs01913237_cn

• Gene Symbol: DTX3
• Assay Reference Genome Location: Chr.12:57608672 on build GRCh38
• Cytoband: 12q13.3

Target Gene Details

• Entrez Gene ID: 196403
• Gene Name: deltex E3 ubiquitin ligase 3
• Gene Aliases: RNF154, deltex3
• Location: Chr.12:57604327-57609804 on Build GRCh38
• Assay Gene Location: Within Exon 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DTX3	NM_001286245.1	5	1259	NP_001273174.1
	NM_001286246.1	5	1278	NP_001273175.1
	NM_178502.3	6	1439	NP_848597.1
	XM_005268697.1	6	1942	XP_005268754.1
	XM_005268698.1	6	1715	XP_005268755.1
	XM_005268700.1	6	1595	XP_005268757.1
	XM_005268703.1	6	1614	XP_005268760.1
	XM_011538022.2	5	1817	XP_011536324.1
	AK092085.1	6	1240	BAC03801.1
	AK094385.1	5	1048	BAC04344.1
	AK128752.1	4	2407
	AY225126.1	3	952	AAP57520.1
	BC114441.1	5	1168
	BC114498.1	5	1168

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv559034	Chr.12:57466149 - 57618450 on Build GRCh38	Loss	ARHGEF25 MIR6758 DDIT3 KIF5A LOC101927583 DCTN2 MBD6 PIP4K2C GLI1 DTX3 MARS ARHGAP9 MIR616
nsv482992	Chr.12:56206217 - 57706217 on Build GRCh38	Gain+Loss	SPRYD4 STAT2 MIR6758 ZBTB39 LRP1 NDUFA4L2 TAC3 INHBE ATP5B LOC101927583 SNORD59B DCTN2 NXPH4 PAN2 MIR1228 PTGES3 SHMT2 INHBC ARHGEF25 NEMP1 DDIT3 NABP2 NACA SNORA105C STAT6 PIP4K2C COQ10A B4GALNT1 GPR182 RBMS2 PRIM1 MIR616 GLS2 SNORD59A RNF41 SDR9C7 RDH16 OS9 HSD17B6 IL23A MARS NAB2 LRP1-AS CNPY2 HBCBP STAC3 KIF5A TIMELESS SLC39A5 R3HDM2 MIP MYO1A SLC26A10 ANKRD52 MBD6 GLI1 DTX3 BAZ2A CS APOF ARHGAP9

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

Notch signaling pathway
protein ubiquitination

Function(s)

protein binding
zinc ion binding
ligase activity