Hs01924329_cn

• Gene Symbol: MADD
• Assay Reference Genome Location: Chr.11:47269464 on build GRCh38
• Cytoband: 11p11.2

Target Gene Details

• Entrez Gene ID: 8567
• Gene Name: MAP kinase activating death domain
• Gene Aliases: DENN, IG20, RAB3GEP
• Location: Chr.11:47269376-47330031 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MADD	NM_130470.2	1	89	NP_569826.2
	DA187733.1	1	89
	U77352.1			AAB57735.1

More Information

Additional Information:

For this assay, SNP(s) [rs116869426] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, non-DGV Variation

Gene Ontology Categories:

Process(es)

activation of MAPK activity
cell surface receptor signaling pathway
regulation of tumor necrosis factor-mediated signaling pathway
regulation of Rab protein signal transduction
regulation of apoptotic process
positive regulation of GTPase activity
regulation of cell cycle
execution phase of apoptosis
regulation of extrinsic apoptotic signaling pathway via death domain receptors
regulation of extrinsic apoptotic signaling pathway

Function(s)

death receptor binding
protein binding
Rab guanyl-nucleotide exchange factor activity
protein kinase activator activity