Hs01933934_cn

• Gene Symbol: TRADD
• Assay Reference Genome Location: Chr.16:67155811 on build GRCh38
• Cytoband: 16q22.1

Target Gene Details

• Entrez Gene ID: 8717
• Gene Name: TNFRSF1A associated via death domain
• Gene Aliases: Hs.89862
• Location: Chr.16:67154185-67159909 on Build GRCh38
• Assay Gene Location: Within Exon 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TRADD	NM_001323552.1			NP_001310481.1
	NM_003789.3			NP_003780.1
	XM_005256213.3	3	592	XP_005256270.1
	XM_017023815.1			XP_016879304.1
	AK090673.1	1	439
	AK301593.1	3	610
	AK315654.1
	BC004491.2			AAH04491.1
	BG717460.1
	BT006934.1			AAP35580.1
	DA353575.1
	L41690.1			AAA98482.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv522852	Chr.16:67153308 - 68071571 on Build GRCh38	Gain	NUTF2 LRRC36 KCTD19 HSD11B2 CTCF AGRP SLC9A5 LOC100505942 RANBP10 NOL3 SLC12A4 TSNAXIP1 PARD6A ELMO3 NRN1L DUS2 TRADD FHOD1 LOC107984813 C16orf86 LRRC29 CARMIL2 LOC100131303 EXOC3L1 HSF4 DPEP3 ACD LOC105369155 PSKH1 ZDHHC1 DPEP2 MIR328 ATP6V0D1 FBXL8 GFOD2 CENPT CTRL KIAA0895L PLEKHG4 LCAT ENKD1 TPPP3 EDC4 PSMB10 E2F4 THAP11 TMEM208 DDX28 FAM65A
nsv827707	Chr.16:67148355 - 67289296 on Build GRCh38	Loss	EXOC3L1 HSF4 C16orf70 TRADD FHOD1 B3GNT9 LOC105369155 MIR328 LRRC29 SLC9A5 FBXL8 NOL3 E2F4 TMEM208 KIAA0895L ELMO3 PLEKHG4
nsv952044	Chr.16:67141198 - 67244397 on Build GRCh38	Deletion	EXOC3L1 HSF4 C16orf70 TRADD FHOD1 B3GNT9 LOC105369155 MIR328 LRRC29 FBXL8 NOL3 E2F4 TMEM208 KIAA0895L ELMO3
nsv524363	Chr.16:67136529 - 68071571 on Build GRCh38	Loss	NUTF2 LRRC36 KCTD19 HSD11B2 CTCF AGRP SLC9A5 LOC100505942 RANBP10 NOL3 SLC12A4 TSNAXIP1 PARD6A ELMO3 NRN1L DUS2 TRADD FHOD1 B3GNT9 LOC107984813 C16orf86 LRRC29 CARMIL2 LOC100131303 EXOC3L1 HSF4 C16orf70 DPEP3 ACD LOC105369155 PSKH1 ZDHHC1 DPEP2 MIR328 ATP6V0D1 FBXL8 GFOD2 CENPT CTRL KIAA0895L PLEKHG4 LCAT ENKD1 TPPP3 EDC4 PSMB10 E2F4 THAP11 TMEM208 DDX28 FAM65A

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
signal transduction
I-kappaB kinase/NF-kappaB signaling
extrinsic apoptotic signaling pathway via death domain receptors
regulation of tumor necrosis factor-mediated signaling pathway
regulation of necrotic cell death
tumor necrosis factor-mediated signaling pathway
positive regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of NF-kappaB transcription factor activity
protein heterooligomerization
positive regulation of hair follicle development
death-inducing signaling complex assembly
extrinsic apoptotic signaling pathway
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

Function(s)

signal transducer activity
tumor necrosis factor receptor binding
protein binding
kinase binding
protein complex binding
identical protein binding
binding, bridging
death domain binding