Hs01969002_cn

• Gene Symbol: CTLA4
• Assay Reference Genome Location: Chr.2:203870604 on build GRCh38
• Cytoband: 2q33.2

Target Gene Details

• Entrez Gene ID: 1493
• Gene Name: cytotoxic T-lymphocyte associated protein 4
• Gene Aliases: ALPS5, CD, CD152, CELIAC3, CTLA-4, GRD4, GSE, IDDM12
• Location: Chr.2:203867788-203873960 on Build GRCh38
• Assay Gene Location: Overlaps Intron 1 - Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CTLA4	NM_001037631.2			NP_001032720.1
	NM_005214.4			NP_005205.2
	AF414120.1			AAL07473.1
	AF486806.1			AAL96664.1
	AK313732.1
	AY209009.1			AAO17066.1
	AY792514.1			AAV66331.1
	AY999702.1			AAY00166.1
	BC069566.1			AAH69566.1
	BC070162.1			AAH70162.1
	BC074842.2			AAH74842.1
	BC074893.2			AAH74893.1
	CD639535.1
	DQ785106.1
	L15006.1			AAB59385.1
	U90273.1			AAD00698.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1001799	Chr.2:202908732 - 205615330 on Build GRCh38	Gain	CYP20A1 WDR12 PARD3B RAPH1 CD28 CTLA4 CARF ABI2 NBEAL1 ICOS RPL12P16

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

immunoglobulin receptor superfamily

Gene Ontology Categories:

Process(es)

adaptive immune response
immune response
cellular response to DNA damage stimulus
negative regulation of B cell proliferation
T cell costimulation
positive regulation of apoptotic process
negative regulation of regulatory T cell differentiation
B cell receptor signaling pathway

Function(s)

protein binding