Hs01998635_cn

• Gene Symbol: KLF11
• Assay Reference Genome Location: Chr.2:10048578 on build GRCh38
• Cytoband: 2p25.1

Target Gene Details

• Entrez Gene ID: 8462
• Gene Name: Kruppel like factor 11
• Gene Aliases: FKLF, FKLF1, MODY7, TIEG2, Tieg3
• Location: Chr.2:10043555-10054836 on Build GRCh38
• Assay Gene Location: Overlaps Exon 5 - Intron 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
KLF11	NM_001177716.1			NP_001171187.1
	NM_001177718.1			NP_001171189.1
	NM_003597.4			NP_003588.1
	AF028008.1			AAC61880.1
	AF272830.1			AAF75793.1
	AJ275989.1			CAC06699.1
	AK289816.1
	AK302880.1
	AK315345.1
	AK316439.1
	BC063286.1			AAH63286.1
	BC069383.1			AAH69383.1
	BC074922.2			AAH74922.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv828308	Chr.2:10035398 - 10060201 on Build GRCh38	Gain	CYS1 LOC101929882 KLF11
nsv508826	Chr.2:10002595 - 10050858 on Build GRCh38	Insertion	LOC101929882 KLF11
nsv828297	Chr.2:9969170 - 10096205 on Build GRCh38	Loss	CYS1 GRHL1 LOC101929882 KLF11
dgv3715n100	Chr.2:10014833 - 10135998 on Build GRCh38	Gain	CYS1 LOC101929882 RRM2 KLF11

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

C2H2 zinc finger transcription factor

Gene Ontology Categories:

Process(es)

regulation of transcription involved in G1/S transition of mitotic cell cycle
negative regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
apoptotic process
negative regulation of cell proliferation
positive regulation of apoptotic process

Function(s)

RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription regulatory region DNA binding
metal ion binding