Hs02018969_cn

• Gene Symbol: TRADD
• Assay Reference Genome Location: Chr.16:67155650 on build GRCh38
• Cytoband: 16q22.1

Target Gene Details

• Entrez Gene ID: 8717
• Gene Name: TNFRSF1A associated via death domain
• Gene Aliases: Hs.89862
• Location: Chr.16:67154185-67159909 on Build GRCh38
• Assay Gene Location: Within Exon 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TRADD	NM_001323552.1			NP_001310481.1
	NM_003789.3			NP_003780.1
	XM_005256213.3	3	753	XP_005256270.1
	XM_017023815.1			XP_016879304.1
	AK090673.1	1	600
	AK301593.1	3	771
	AK315654.1
	BC004491.2			AAH04491.1
	BG717460.1
	BT006934.1			AAP35580.1
	DA353575.1
	L41690.1			AAA98482.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv522852	Chr.16:67153308 - 68071571 on Build GRCh38	Gain	NRN1L ZDHHC1 EDC4 PSKH1 NOL3 NUTF2 TRADD TPPP3 PLEKHG4 LOC100131303 DUS2 FHOD1 GFOD2 CENPT CTRL ENKD1 HSF4 SLC12A4 LOC107984813 TMEM208 KIAA0895L DPEP2 ACD ATP6V0D1 LCAT THAP11 C16orf86 FAM65A LOC100505942 E2F4 CARMIL2 LRRC29 KCTD19 HSD11B2 ELMO3 AGRP LRRC36 RANBP10 LOC105369155 MIR328 EXOC3L1 DPEP3 CTCF TSNAXIP1 PSMB10 SLC9A5 PARD6A FBXL8 DDX28
nsv827707	Chr.16:67148355 - 67289296 on Build GRCh38	Loss	HSF4 LRRC29 NOL3 TRADD TMEM208 SLC9A5 KIAA0895L ELMO3 B3GNT9 C16orf70 PLEKHG4 LOC105369155 MIR328 FBXL8 E2F4 EXOC3L1 FHOD1
nsv952044	Chr.16:67141198 - 67244397 on Build GRCh38	Deletion	HSF4 LRRC29 NOL3 TRADD TMEM208 KIAA0895L ELMO3 B3GNT9 C16orf70 LOC105369155 MIR328 FBXL8 E2F4 EXOC3L1 FHOD1
nsv524363	Chr.16:67136529 - 68071571 on Build GRCh38	Loss	NRN1L ZDHHC1 EDC4 PSKH1 NOL3 NUTF2 TRADD TPPP3 PLEKHG4 LOC100131303 DUS2 FHOD1 GFOD2 CENPT CTRL ENKD1 HSF4 SLC12A4 LOC107984813 TMEM208 KIAA0895L DPEP2 ACD ATP6V0D1 LCAT B3GNT9 THAP11 C16orf86 FAM65A LOC100505942 E2F4 CARMIL2 LRRC29 KCTD19 HSD11B2 ELMO3 AGRP LRRC36 RANBP10 LOC105369155 MIR328 EXOC3L1 DPEP3 CTCF TSNAXIP1 PSMB10 SLC9A5 PARD6A C16orf70 FBXL8 DDX28

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
signal transduction
I-kappaB kinase/NF-kappaB signaling
extrinsic apoptotic signaling pathway via death domain receptors
regulation of tumor necrosis factor-mediated signaling pathway
regulation of necrotic cell death
tumor necrosis factor-mediated signaling pathway
positive regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of NF-kappaB transcription factor activity
protein heterooligomerization
positive regulation of hair follicle development
death-inducing signaling complex assembly
extrinsic apoptotic signaling pathway
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

Function(s)

signal transducer activity
tumor necrosis factor receptor binding
protein binding
kinase binding
protein complex binding
identical protein binding
binding, bridging
death domain binding