Hs02039130_cn

• Gene Symbol: E2F4
• Assay Reference Genome Location: Chr.16:67198620 on build GRCh38
• Cytoband: 16q22.1

Target Gene Details

• Entrez Gene ID: 1874
• Gene Name: E2F transcription factor 4
• Gene Aliases: E2F-4
• Location: Chr.16:67192165-67198918 on Build GRCh38
• Assay Gene Location: Within Exon 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
E2F4	NM_001950.3	10	1802	NP_001941.2
	BC033180.1	10	1755	AAH33180.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv522852	Chr.16:67153308 - 68071571 on Build GRCh38	Gain	DPEP2 FAM65A KCTD19 C16orf86 ATP6V0D1 LCAT TMEM208 NOL3 EXOC3L1 HSD11B2 ENKD1 CENPT ACD LRRC29 KIAA0895L CARMIL2 LOC100131303 TRADD FHOD1 EDC4 LOC105369155 GFOD2 DDX28 SLC12A4 TPPP3 DPEP3 RANBP10 CTRL LOC100505942 ZDHHC1 DUS2 SLC9A5 LOC107984813 CTCF FBXL8 MIR328 AGRP E2F4 NUTF2 PSMB10 ELMO3 TSNAXIP1 THAP11 PSKH1 NRN1L PLEKHG4 HSF4 LRRC36 PARD6A
nsv827707	Chr.16:67148355 - 67289296 on Build GRCh38	Loss	TRADD SLC9A5 FHOD1 ELMO3 FBXL8 LOC105369155 MIR328 C16orf70 TMEM208 B3GNT9 NOL3 EXOC3L1 E2F4 LRRC29 KIAA0895L PLEKHG4 HSF4
nsv952044	Chr.16:67141198 - 67244397 on Build GRCh38	Deletion	TRADD FHOD1 ELMO3 FBXL8 LOC105369155 MIR328 C16orf70 TMEM208 B3GNT9 NOL3 EXOC3L1 E2F4 LRRC29 KIAA0895L HSF4
nsv1160429	Chr.16:67161549 - 67220197 on Build GRCh38	Deletion	NOL3 EXOC3L1 E2F4 LRRC29 KIAA0895L ELMO3 FBXL8 HSF4 LOC105369155 MIR328
nsv457513	Chr.16:67181417 - 67282697 on Build GRCh38	Loss	TMEM208 EXOC3L1 SLC9A5 E2F4 LRRC29 FHOD1 KIAA0895L ELMO3 PLEKHG4 LOC105369155 MIR328
nsv524492	Chr.16:67174030 - 67294550 on Build GRCh38	Loss	SLC9A5 KCTD19 FHOD1 ELMO3 LOC105369155 MIR328 TMEM208 NOL3 EXOC3L1 E2F4 LRRC29 KIAA0895L PLEKHG4
nsv524363	Chr.16:67136529 - 68071571 on Build GRCh38	Loss	DPEP2 FAM65A KCTD19 C16orf86 C16orf70 ATP6V0D1 LCAT TMEM208 NOL3 EXOC3L1 HSD11B2 ENKD1 CENPT ACD LRRC29 KIAA0895L CARMIL2 LOC100131303 TRADD FHOD1 EDC4 LOC105369155 GFOD2 DDX28 SLC12A4 TPPP3 DPEP3 RANBP10 CTRL LOC100505942 ZDHHC1 DUS2 SLC9A5 LOC107984813 CTCF FBXL8 MIR328 AGRP E2F4 NUTF2 PSMB10 ELMO3 TSNAXIP1 B3GNT9 THAP11 PSKH1 NRN1L PLEKHG4 HSF4 LRRC36 PARD6A

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA metabolism protein, nucleic acid metabolism protein, general transcription factor

Gene Ontology Categories:

Process(es)

regulation of transcription involved in G1/S transition of mitotic cell cycle
epithelial cell development
transcription from RNA polymerase II promoter
cell volume homeostasis
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
blood circulation
organ morphogenesis
regulation of cell proliferation
motile cilium assembly
positive regulation of transcription from RNA polymerase II promoter
centriole assembly
multi-ciliated epithelial cell differentiation

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription factor binding
protein domain specific binding
promoter-specific chromatin binding