Hs02056912_cn

• Gene Symbol: TPPP
• Assay Reference Genome Location: Chr.5:665267 on build GRCh38
• Cytoband: 5p15.33

Target Gene Details

• Entrez Gene ID: 11076
• Gene Name: tubulin polymerization promoting protein
• Gene Aliases: TPPP/p25, TPPP1, p24, p25, p25alpha
• Location: Chr.5:659862-730454 on Build GRCh38
• Assay Gene Location: Overlaps Intron 8 - Exon 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TPPP	NM_007030.2			NP_008961.1
	XM_005248237.3			XP_005248294.2
	XM_017008993.1			XP_016864482.1
	XM_017008994.1			XP_016864483.1
	AB017016.1			BAA36164.1
	AK054920.1
	AK098392.1
	AY319261.1			AAQ96657.1
	BC040496.1			AAH40496.1
	BC131506.1
	BC152382.1
	BT020035.1			AAV38838.1
	DB478250.2

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv5521n100	Chr.5:568570 - 685633 on Build GRCh38	Gain	LOC101929895 CEP72 TPPP LOC100996325
esv3894107	Chr.5:81322 - 801057 on Build GRCh38	Gain	LOC101929895 CEP72 SLC9A3 PLEKHG4B LOC100288152 SDHA TPPP ZDHHC11B PDCD6 AHRR LOC100996325 LRRC14B EXOC3-AS1 HRAT5 ZDHHC11 CCDC127 EXOC3 PP7080 MIR4456
nsv4675	Chr.5:658779 - 844631 on Build GRCh38	Deletion	LOC101929895 CEP72 ZDHHC11 TPPP ZDHHC11B
nsv1032584	Chr.5:375290 - 809679 on Build GRCh38	Gain	LOC101929895 CEP72 SLC9A3 LOC100288152 TPPP ZDHHC11B AHRR LOC100996325 EXOC3-AS1 ZDHHC11 EXOC3 PP7080 MIR4456
esv2759316	Chr.5:620048 - 1161361 on Build GRCh38	Gain+Loss	LOC101929895 CEP72 NKD2 BRD9 ZDHHC11 TPPP ZDHHC11B TRIP13 MIR4635 LOC100506688 SLC12A7
dgv7n29	Chr.5:609831 - 820394 on Build GRCh38	Gain	LOC101929895 CEP72 ZDHHC11 TPPP ZDHHC11B LOC100996325
nsv1033593	Chr.5:609765 - 685633 on Build GRCh38	Gain	LOC101929895 CEP72 TPPP LOC100996325
nsv596703	Chr.5:539195 - 685633 on Build GRCh38	Gain	LOC101929895 CEP72 TPPP LOC100996325
nsv596629	Chr.5:457146 - 1468172 on Build GRCh38	Gain	LOC100288152 TPPP CTD-3080P12.3 NKD2 MIR4457 LPCAT1 ZDHHC11 LINC01511 SLC6A18 EXOC3 PP7080 MIR4456 SLC12A7 LOC101929895 CEP72 SLC9A3 TERT ZDHHC11B LOC100996325 SLC6A3 CLPTM1L BRD9 SLC6A19 TRIP13 MIR4635 LOC100506688
nsv471627	Chr.5:609832 - 826405 on Build GRCh38	Gain+Loss	LOC101929895 CEP72 ZDHHC11 TPPP ZDHHC11B LOC100996325
nsv509042	Chr.5:483833 - 720373 on Build GRCh38	Insertion	LOC101929895 CEP72 SLC9A3 TPPP ZDHHC11B LOC100996325 MIR4456
nsv950622	Chr.5:661486 - 693585 on Build GRCh38	Deletion	LOC101929895 CEP72 TPPP
nsv1161198	Chr.5:654181 - 817735 on Build GRCh38	Duplication	LOC101929895 CEP72 ZDHHC11 TPPP ZDHHC11B
esv3575804	Chr.5:588315 - 676732 on Build GRCh38	Gain	LOC101929895 CEP72 TPPP LOC100996325
dgv922n67	Chr.5:662068 - 788975 on Build GRCh38	Gain	LOC101929895 CEP72 TPPP ZDHHC11B
dgv195e55	Chr.5:659490 - 823705 on Build GRCh38	Gain	LOC101929895 CEP72 ZDHHC11 TPPP ZDHHC11B
dgv5522n100	Chr.5:625176 - 809679 on Build GRCh38	Gain	LOC101929895 CEP72 ZDHHC11 TPPP ZDHHC11B
nsv596710	Chr.5:595755 - 729907 on Build GRCh38	Gain	LOC101929895 CEP72 TPPP ZDHHC11B LOC100996325
dgv131e203	Chr.5:653466 - 874903 on Build GRCh38	Gain+Loss	LOC101929895 CEP72 BRD9 ZDHHC11 TPPP ZDHHC11B
esv2752071	Chr.5:378298 - 699075 on Build GRCh38	Gain	LOC101929895 EXOC3-AS1 CEP72 SLC9A3 LOC100288152 TPPP EXOC3 AHRR PP7080 LOC100996325 MIR4456
dgv5524n100	Chr.5:659283 - 825526 on Build GRCh38	Gain	LOC101929895 CEP72 ZDHHC11 TPPP ZDHHC11B
dgv5523n100	Chr.5:653454 - 790474 on Build GRCh38	Gain	LOC101929895 CEP72 TPPP ZDHHC11B
nsv461894	Chr.5:593968 - 685633 on Build GRCh38	Gain	LOC101929895 CEP72 TPPP LOC100996325

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-motor microtubule binding protein

Gene Ontology Categories:

Process(es)

microtubule bundle formation
positive regulation of protein complex assembly
positive regulation of protein polymerization
microtubule polymerization

Function(s)

protein binding
microtubule binding
tubulin binding