Hs02061917_cn

• Gene Symbol: DTX3
• Assay Reference Genome Location: Chr.12:57605626 on build GRCh38
• Cytoband: 12q13.3

Target Gene Details

• Entrez Gene ID: 196403
• Gene Name: deltex E3 ubiquitin ligase 3
• Gene Aliases: RNF154, deltex3
• Location: Chr.12:57604327-57609804 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DTX3	NM_001286245.1			NP_001273174.1
	NM_001286246.1			NP_001273175.1
	NM_178502.3	2	293	NP_848597.1
	XM_005268697.1	2	815	XP_005268754.1
	XM_005268698.1	2	588	XP_005268755.1
	XM_005268700.1			XP_005268757.1
	XM_005268703.1			XP_005268760.1
	XM_011538022.2	1	671	XP_011536324.1
	AK092085.1	2	94	BAC03801.1
	AK094385.1			BAC04344.1
	AK128752.1	1	803
	AL831941.1	1	620	CAD38593.2
	BC114441.1
	BC114498.1
	DA684401.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv428283	Chr.12:57435950 - 57608085 on Build GRCh38	Gain	MIR6758 MIR616 GLI1 DDIT3 MBD6 DTX3 INHBE MARS DCTN2 KIF5A INHBC ARHGAP9 PIP4K2C
nsv559034	Chr.12:57466149 - 57618450 on Build GRCh38	Loss	MIR6758 MIR616 GLI1 ARHGEF25 DDIT3 MBD6 DTX3 MARS DCTN2 KIF5A ARHGAP9 LOC101927583 PIP4K2C
nsv482992	Chr.12:56206217 - 57706217 on Build GRCh38	Gain+Loss	GLI1 ANKRD52 DDIT3 TAC3 DTX3 B4GALNT1 GLS2 LRP1-AS RDH16 SNORD59A PAN2 LOC101927583 PIP4K2C TIMELESS MIR616 CNPY2 RBMS2 NAB2 MBD6 INHBE MIP MARS ATP5B SDR9C7 BAZ2A KIF5A PTGES3 SLC26A10 HBCBP ARHGAP9 SPRYD4 NEMP1 PRIM1 NXPH4 SNORD59B ARHGEF25 R3HDM2 SHMT2 COQ10A DCTN2 MYO1A NABP2 LRP1 STAT2 SNORA105C STAC3 MIR6758 NDUFA4L2 OS9 ZBTB39 IL23A GPR182 HSD17B6 APOF SLC39A5 INHBC CS NACA STAT6 RNF41 MIR1228

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

Notch signaling pathway
protein ubiquitination

Function(s)

protein binding
zinc ion binding
ligase activity