Hs02086709_cn

• Gene Symbol: GRB7
• Assay Reference Genome Location: Chr.17:39742575 on build GRCh38
• Cytoband: 17q12

Target Gene Details

• Entrez Gene ID: 2886
• Gene Name: growth factor receptor bound protein 7
• Gene Aliases: -
• Location: Chr.17:39737909-39747285 on Build GRCh38
• Assay Gene Location: Overlaps Intron 5 - Exon 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GRB7	NM_001030002.2			NP_001025173.1
	NM_001242442.1			NP_001229371.1
	NM_001242443.1			NP_001229372.1
	NM_005310.3			NP_005301.2
	XM_017024536.1			XP_016880025.1
	XM_017024537.1			XP_016880026.1
	XM_017024538.1			XP_016880027.1
	AB008789.1			BAA29059.1
	AB008790.1			BAA29060.1
	AK027729.1
	AK125544.1
	AK222849.1			BAD96569.1
	AK222870.1			BAD96590.1
	AK290115.1
	AK294620.1
	AK314368.1
	AU124875.1
	BC006535.2			AAH06535.1
	BT006686.1			AAP35332.1
	D43772.1			BAA07827.1
	D87513.1			BAA13412.1
	DC384178.1
	KU178103.1
	KU178104.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv953895	Chr.17:39730748 - 39746847 on Build GRCh38	Deletion	GRB7
nsv1056234	Chr.17:39706352 - 39753735 on Build GRCh38	Gain	MIEN1 ERBB2 MIR4728 GRB7
nsv2048	Chr.17:39718682 - 39742588 on Build GRCh38	Insertion	MIEN1 ERBB2 MIR4728 GRB7

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

epidermal growth factor receptor signaling pathway
positive regulation of signal transduction
negative regulation of translation
positive regulation of cell migration
stress granule assembly
ERBB2 signaling pathway
leukocyte migration

Function(s)

RNA binding
SH3/SH2 adaptor activity
protein binding
protein kinase binding
phosphatidylinositol binding
identical protein binding