Hs02092199_cn

• Gene Symbol: MTA2
• Assay Reference Genome Location: Chr.11:62600227 on build GRCh38
• Cytoband: 11q12.3

Target Gene Details

• Entrez Gene ID: 9219
• Gene Name: metastasis associated 1 family member 2
• Gene Aliases: MTA1L1, PID
• Location: Chr.11:62593203-62601840 on Build GRCh38
• Assay Gene Location: Overlaps Intron 3 - Exon 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MTA2	NM_004739.3			NP_004730.2
	XM_017018561.1			XP_016874050.1
	AB016591.1			BAA36707.1
	AF295807.1			AAG02241.1
	AK301569.1
	AL561056.3
	BC023656.2			AAH23656.1
	BC053650.1			AAH53650.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3584599	Chr.11:62495270 - 62630578 on Build GRCh38	Gain	GANAB B3GAT3 AHNAK TUT1 EML3 ROM1 EEF1G MIR6747 MTA2
nsv825939	Chr.11:62558611 - 62643105 on Build GRCh38	Gain	GANAB B3GAT3 TUT1 EML3 ROM1 EEF1G MIR6747 MTA2
nsv832182	Chr.11:62528103 - 62695376 on Build GRCh38	Gain+Loss	HNRNPUL2-BSCL2 C11orf98 LBHD1 B3GAT3 INTS5 UQCC3 UBXN1 METTL12 LRRN4CL GANAB AHNAK SNORA57 TUT1 EML3 BSCL2 ROM1 EEF1G MIR6747 MTA2
esv3579735	Chr.11:62599422 - 62608458 on Build GRCh38	Loss	EML3 MTA2
nsv555174	Chr.11:62566624 - 62729047 on Build GRCh38	Gain	HNRNPUL2-BSCL2 C11orf98 HNRNPUL2 LBHD1 B3GAT3 INTS5 GNG3 UQCC3 UBXN1 METTL12 TTC9C LRRN4CL GANAB SNORA57 TUT1 EML3 BSCL2 ROM1 EEF1G MIR6747 MTA2

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

homeodomain transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
DNA methylation
chromatin assembly or disassembly
regulation of fibroblast migration
histone deacetylation
ATP-dependent chromatin remodeling
positive regulation of transcription from RNA polymerase II promoter
regulation of signal transduction by p53 class mediator

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
transcription factor activity, transcription factor binding
RNA polymerase II transcription factor binding
RNA polymerase II repressing transcription factor binding
transcription factor activity, sequence-specific DNA binding
histone deacetylase activity
protein binding
zinc ion binding
nucleosomal DNA binding
histone deacetylase binding