Hs02102413_cn

• Gene Symbol: TRPV4
• Assay Reference Genome Location: Chr.12:109803126 on build GRCh38
• Cytoband: 12q24.11

Target Gene Details

• Entrez Gene ID: 59341
• Gene Name: transient receptor potential cation channel subfamily V member 4
• Gene Aliases: BCYM3, CMT2C, HMSN2C, OTRPC4, SMAL, SPSMA, SSQTL1, TRP12, VRL2, VROAC
• Location: Chr.12:109783087-109833407 on Build GRCh38
• Assay Gene Location: Overlaps Intron 6 - Exon 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TRPV4	NM_001177428.1			NP_001170899.1
	NM_001177431.1			NP_001170902.1
	NM_001177433.1			NP_001170904.1
	NM_021625.4			NP_067638.3
	NM_147204.2			NP_671737.1
	XM_005253918.1			XP_005253975.1
	XM_011538630.2			XP_011536932.2
	XM_011538631.2			XP_011536933.2
	XM_011538632.2			XP_011536934.2
	XM_011538633.2			XP_011536935.2
	XM_011538634.2			XP_011536936.2
	XM_011538635.2			XP_011536937.1
	XM_011538636.2			XP_011536938.1
	XM_017019774.1			XP_016875263.1
	AB032427.1			BAB69040.1
	AB073669.1			BAC06573.1
	AB100308.1			BAC55864.1
	AF258465.1			AAG16127.1
	AF263523.1			AAG28029.1
	AF279673.1			AAK69487.1
	AJ296305.1			CAC82937.1
	AL834192.1
	BC117426.1
	BC143315.1
	DQ059644.1			AAZ04918.1
	DQ059645.1			AAZ04919.1
	DQ059646.1			AAZ04920.1

More Information

• Set Membership: Intragenic, Non-exonic, non-DGV Variation

Panther Classification:

Molecular Function -

ion channel

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
diet induced thermogenesis
calcium ion transport
cellular calcium ion homeostasis
cell volume homeostasis
actin filament organization
cell-cell junction assembly
positive regulation of cytosolic calcium ion concentration
osmosensory signaling pathway
response to mechanical stimulus
positive regulation of gene expression
positive regulation of macrophage chemotaxis
negative regulation of neuron projection development
vasopressin secretion
positive regulation of microtubule depolymerization
actin cytoskeleton reorganization
response to insulin
cellular response to heat
hyperosmotic salinity response
glucose homeostasis
positive regulation of vascular permeability
cortical microtubule organization
positive regulation of JNK cascade
microtubule polymerization
regulation of response to osmotic stress
positive regulation of inflammatory response
multicellular organismal water homeostasis
positive regulation of ERK1 and ERK2 cascade
calcium ion import
calcium ion transmembrane transport
cellular response to osmotic stress
cellular hypotonic response
cellular hypotonic salinity response
positive regulation of monocyte chemotactic protein-1 production
positive regulation of macrophage inflammatory protein 1 alpha production
positive regulation of chemokine (C-C motif) ligand 5 production
blood vessel endothelial cell delamination
negative regulation of brown fat cell differentiation
signal transduction involved in regulation of aerobic respiration
positive regulation of chemokine (C-X-C motif) ligand 1 production
positive regulation of energy homeostasis
positive regulation of interleukin-6 secretion

Function(s)

actin binding
osmosensor activity
protein kinase C binding
cation channel activity
calcium channel activity
protein binding
calmodulin binding
ATP binding
microtubule binding
stretch-activated, cation-selective, calcium channel activity
protein kinase binding
SH2 domain binding
alpha-tubulin binding
beta-tubulin binding
actin filament binding