Hs02118968_cn

• Gene Symbol: MGST1
• Assay Reference Genome Location: Chr.12:16347148 on build GRCh38
• Cytoband: 12p12.3

Target Gene Details

• Entrez Gene ID: 4257
• Gene Name: microsomal glutathione S-transferase 1
• Gene Aliases: GST12, MGST, MGST-I
• Location: Chr.12:16347142-16377189 on Build GRCh38
• Assay Gene Location: Overlaps - Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MGST1	NM_145792.2			NP_665735.1
	R86750.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1049805	Chr.12:16284461 - 16498558 on Build GRCh38	Loss	MGST1
nsv1036638	Chr.12:15912446 - 16358900 on Build GRCh38	Loss	MGST1 SLC15A5 DERA
esv3892149	Chr.12:16266471 - 16354205 on Build GRCh38	Loss	MGST1 SLC15A5
esv3892150	Chr.12:16339581 - 16384735 on Build GRCh38	Loss	MGST1
nsv832338	Chr.12:16319300 - 16487163 on Build GRCh38	Gain	MGST1

More Information

Additional Information:

• Set Membership: Intragenic, Non-exonic, DGV Variation, Validated

Panther Classification:

Molecular Function -

transferase

Gene Ontology Categories:

Process(es)

glutathione metabolic process
xenobiotic metabolic process
response to organonitrogen compound
response to lipopolysaccharide
Leydig cell differentiation
response to drug
oxidation-reduction process
protein homotrimerization
cellular response to lipid hydroperoxide
cellular oxidant detoxification
glutathione derivative biosynthetic process

Function(s)

glutathione transferase activity
glutathione peroxidase activity
protein binding
protein homodimerization activity
glutathione binding