Hs02153168_cn

• Gene Symbol: NKX2-8
• Assay Reference Genome Location: Chr.14:36580346 on build GRCh38
• Cytoband: 14q13.3

Target Gene Details

• Entrez Gene ID: 26257
• Gene Name: NK2 homeobox 8
• Gene Aliases: NKX2.8, NKX2H, Nkx2-9
• Location: Chr.14:36580011-36582614 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NKX2-8	NM_014360.3	2	1501	NP_055175.2
	BC041090.1	2	1468	AAH41090.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv32575	Chr.14:36578424 - 36583453 on Build GRCh38	Gain	NKX2-8

More Information

Additional Information:

For this assay, SNP(s) [rs74949744] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

homeodomain transcription factor

Gene Ontology Categories:

Process(es)

liver development
transcription, DNA-templated
transcription from RNA polymerase II promoter
axonogenesis
lung development
positive regulation of transcription from RNA polymerase II promoter
negative regulation of epithelial cell proliferation

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
sequence-specific DNA binding